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Ohio vs. Northern Illinois prediction: Ohio favored to win men's college basketball matchup [2/21/2026]

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Written by Dave Garofolo

Get Ohio vs Northern Illinois predictions for college basketball Saturday.

Ohio-Northern Illinois Predictions and Game Preview.
Ohio vs. Northern Illinois men's college basketball prediction for Saturday, February 21, 2026.

Northern Illinois will face the favored Ohio in men's college basketball action at NIU Convocation Center on Saturday, starting at 3:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Ohio as the most likely winner of the Ohio vs. Northern Illinois game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Ohio vs. Northern Illinois prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Ohio and Northern Illinois 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Ohio a 71% chance of beating Northern Illinois. Our predicted final score has Ohio winning 79-73.

According to our model, Ohio (-6.5) has a 51% chance of covering the spread, while the over/under total of 148.5 points has a 52% chance of going over.

 

Ohio vs. Northern Illinois odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Ohio Northern Illinois
Spread -6.5 (-105) +6.5 (-115)
Moneyline -258 +210
Total o148.5 (-112) u148.5 (-106)

All odds are correct at the time of publication and are subject to change.

Ohio vs. Northern Illinois picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Ohio -6.5 -105
Moneyline Ohio -258
Total Over 148.5 -112

According to our men's college basketball best bets, the top play to make on this game is Ohio -6.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Ohio vs. Northern Illinois game-day updates and essential details

Saturday's men's college basketball game between Northern Illinois and Ohio at NIU Convocation Center is scheduled to begin at 3:00 PM ET.

  • Who: Ohio vs. Northern Illinois
  • Date: Saturday, February 21, 2026
  • Time: 3:00 PM ET/12:00PM PT
  • Venue: NIU Convocation Center

Conclusion

We predict Ohio, with a 71% win probability, will likely beat Northern Illinois on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Ohio vs. Northern Illinois insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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