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Iowa vs. Iowa State prediction: Why Iowa State is favored to win women's college basketball matchup [12/10/2025]

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Written by Ryan Leaver

Get Iowa vs Iowa State predictions for college basketball Wednesday.

Iowa-Iowa State Predictions and Game Preview.
Iowa vs. Iowa State women's college basketball prediction for Wednesday, December 10, 2025.

Iowa State and Iowa will meet in the women's college basketball at James H. Hilton Coliseum on Wednesday, starting at 7:00PM ET.

Based on the latest simulations, Dimers' new women's basketball model predicts Iowa State as the most likely winner of the Iowa vs. Iowa State game.

This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.

Iowa vs. Iowa State prediction: Who will win?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's women's basketball matchup between Iowa and Iowa State 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model gives Iowa State a 57% chance of beating Iowa.

According to our model, the over/under total of 149.5 points has a 57% chance of staying under.

 

Iowa vs. Iowa State odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

Bet Type Iowa Iowa State
Spread +4.5 (-105) -4.5 (-115)
Moneyline +160 -168
Total o149.5 (-110) u149.5 (-110)

All odds are correct at the time of publication and are subject to change.

Iowa vs. Iowa State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Iowa +4.5 -105
Moneyline Iowa +160
Total Under 149.5 -110

According to our women's college basketball best bets, the top play to make on this game is Iowa +4.5 at the spread.

 

Iowa vs. Iowa State game-day updates and essential details

Wednesday's women's basketball matchup between Iowa State and Iowa at James H. Hilton Coliseum is scheduled to begin at 7:00PM ET.

  • Who: Iowa vs. Iowa State
  • Date: Wednesday, December 10, 2025
  • Time: 7:00PM ET/4:00PM PT
  • Venue: James H. Hilton Coliseum

Conclusion

We predict Iowa State, with a 57% win probability, will likely beat Iowa on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Iowa vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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