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Iowa vs. Iowa State prediction: Why Iowa State is favored to win women's college basketball matchup [12/10/2025]
Get Iowa vs Iowa State predictions for college basketball Wednesday.

Iowa State will take on Iowa in women's college basketball action at James H. Hilton Coliseum on Wednesday, starting at 7:00PM ET.
Based on updated simulation results, Dimers' new women's basketball model projects Iowa State as the most likely winner of the Iowa vs. Iowa State game.
This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.
Iowa vs. Iowa State prediction: Who will win?
Using powerful machine learning and data analysis, we have simulated the result of Wednesday's women's basketball game between Iowa and Iowa State 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model currently gives Iowa State a 55% chance of defeating Iowa.
According to our model, the 150.5-point over/under has a 60% chance of staying under.
Iowa vs. Iowa State odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Iowa | Iowa State |
|---|---|---|
| Spread | +4.5 (-105) | -4.5 (-115) |
| Moneyline | +160 | -168 |
| Total | o150.5 (-110) | u150.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Iowa vs. Iowa State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Iowa +4.5 | -105 |
| Moneyline | Iowa | +160 |
| Total | Under 150.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Under 150.5 total points.
Iowa vs. Iowa State game-day updates and essential details
Wednesday's women's basketball action between Iowa State and Iowa at James H. Hilton Coliseum is scheduled to start at 7:00PM ET.
- Who: Iowa vs. Iowa State
- Date: Wednesday, December 10, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: James H. Hilton Coliseum
Conclusion
We predict Iowa State, with a 55% win probability, will likely beat Iowa on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Iowa vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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