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Illinois vs. Missouri prediction: Why Illinois is favored to win women's college basketball matchup [12/10/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Illinois vs Missouri predictions for college basketball Wednesday.
Missouri and Illinois are scheduled to meet in the women's college basketball at Mizzou Arena on Wednesday, starting at 7:00PM ET.
Based on updated simulation results, Dimers' new women's basketball model predicts Illinois as the most likely winner of the Illinois vs. Missouri game.
This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.
Illinois vs. Missouri prediction: Who will win?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's women's basketball game between Illinois and Missouri 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Illinois a 77% chance of defeating Missouri.
According to our model, the over/under total of 141.5 points has a 58% chance of staying under.
Illinois vs. Missouri odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Illinois | Missouri |
|---|---|---|
| Spread | -5.5 (-110) | +5.5 (-110) |
| Moneyline | -270 | +225 |
| Total | o141.5 (-110) | u141.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Illinois vs. Missouri picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Illinois -5.5 | -110 |
| Moneyline | Illinois | -270 |
| Total | Under 141.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Under 141.5 total points.
Illinois vs. Missouri game-day updates and essential details
Wednesday's women's basketball game between Missouri and Illinois at Mizzou Arena is scheduled to commence at 7:00PM ET.
- Who: Illinois vs. Missouri
- Date: Wednesday, December 10, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Mizzou Arena
Conclusion
We predict Illinois, with a 77% win probability, will likely beat Missouri on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Illinois vs. Missouri insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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