Detroit Lions vs. Washington Commanders: Experts release early Week 10 predictions [2025]

The Detroit Lions and Washington Commanders will meet in Week 10 of the NFL season at Northwest Stadium on Sunday, November 9, 2025, starting at 4:25PM ET.

Early simulations from Dimers' trusted NFL model favor the Lions as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Lions vs. Commanders predictions page.

Detroit vs. Washington early predictions

Leveraging trusted machine learning and analysis, we have simulated the Lions vs. Commanders game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Lions 73%, Commanders 27%
• Predicted final score: Lions 28-21 Commanders
• Spread: Lions (-8.5) 43%, Commanders (+8.5) 57%
• Total points (49.5): Over 50%, Under 50%

As of November 3, 2025, these Lions-Commanders numbers and predictions reflect the latest data and insights available.

Lions vs. Commanders Week 10 details

The NFL Week 10 action between the Commanders and Lions at Northwest Stadium is scheduled for November 9, 2025.

• Who: Detroit Lions vs. Washington Commanders
• Date: Sunday, November 9, 2025
• Time: 4:25PM ET/1:25PM PT
• Venue: Northwest Stadium

Lions vs. Commanders opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Lions -8.5 (-110), Commanders +8.5 (-108)
• Moneyline: Lions -480, Commanders +390
• Total: Over/Under 49.5 (-108/-110)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 10 highlight the top candidates to score a TD in Lions-Commanders in Week 10:

Detroit Lions

• Jahmyr Gibbs: 67.2% probability
• Amon-Ra St. Brown: 52.9% probability
• David Montgomery: 50.1% probability

Washington Commanders

• Jacory Croskey-Merritt: 44.4% probability
• Deebo Samuel: 37.8% probability
• Zach Ertz: 33.0% probability

Lions vs Commanders player props

Jahmyr Gibbs is projected to lead rushing for the Lions, while Jacory Croskey-Merritt is expected to pace the Commanders on the ground.

In the receiving game, our projections favor Detroit's Amon-Ra St. Brown and Washington's Deebo Samuel as the likely leaders for each team.

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Conclusion

We predict the Lions, with a 73% win probability, will likely beat the Commanders in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Lions vs. Commanders matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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