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UConn vs. USC prediction: Connecticut favored to win women's college basketball matchup [12/13/2025]
Get UConn vs USC predictions for college basketball Saturday.

USC will take on the favored UConn in women's college basketball action at Galen Center on Saturday, commencing at 5:30PM ET.
Based on the latest simulation results, Dimers' new women's basketball model predicts Connecticut as the most likely winner of the UConn vs. USC game.
This article offers a closer look at Saturday's matchup, including best bets and picks.
UConn vs. USC prediction: Who will win?
Using powerful machine learning and data analysis, we have simulated the result of Saturday's women's basketball matchup between UConn and USC 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model currently gives Connecticut a 93% chance of beating USC.
According to our model, the 131.5-point over/under has a 55% chance of going over.
UConn vs. USC odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | UConn | USC |
|---|---|---|
| Spread | -20.5 (-110) | +20.5 (-110) |
| Moneyline | -3226 | +1400 |
| Total | o131.5 (-110) | u131.5 (-110) |
All odds are correct at the time of publication and are subject to change.
UConn vs. USC picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | USC +20.5 | -110 |
| Moneyline | USC | +1400 |
| Total | Over 131.5 | -110 |
According to our best women's college basketball bets, the top play to make on this game is USC +20.5 at the spread.
UConn vs. USC game-day updates and essential details
Saturday's women's basketball action between USC and UConn at Galen Center is scheduled to commence at 5:30PM ET.
- Who: Connecticut vs. USC
- Date: Saturday, December 13, 2025
- Time: 5:30PM ET/2:30PM PT
- Venue: Galen Center
Conclusion
We predict Connecticut, with a 93% win probability, will likely beat USC on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Connecticut vs. USC insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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