Best bets today for all sports: Wednesday's picks include St. Francis (PA) vs. Florida men's college basketball play [12/17/2025]

Men's College Basketball: St. Francis (PA) +45.5 (-110)

• Edge: 9.6%
• Probability: 62%
• Men's College Basketball matchup: St. Francis (PA) vs. Florida (6:30PM ET, Wednesday)

Our model has identified value on St. Francis (PA) +45.5 at -110 odds. A 62% probability produces an edge of 9.6%, making this the strongest play for today's sports action.

Men's College Basketball: Louisiana Tech +3.5 (-108)

• Edge: 6.5%
• Probability: 58.4%
• Men's College Basketball matchup: Louisiana Tech vs. Tulane (7:30PM ET, Wednesday)

Louisiana Tech +3.5 carries a 6.5% edge and a probability of 58.4% at -108 odds, according to our model.

Men's College Basketball: Santa Clara -11.5 (-105)

• Edge: 6.4%
• Probability: 57.6%
• Men's College Basketball Matchup: North Texas vs. Santa Clara (9:00PM ET, Wednesday)

Santa Clara -11.5 vs. North Texas at -105 odds shows a 6.4% edge, supported by a 57.6% probability in simulations.

Men's College Basketball: Vermont ML (-118)

• Edge: 5.9%
• Probability: 60.1%
• Men's College Basketball Matchup: Siena vs. Vermont (7:00PM ET, Wednesday)

A 5.9% edge and 60.1% probability make Vermont at the moneyline at a value play in the Siena vs. Vermont matchup, per our model.

College Football: South Florida -2.5 (-114)

• Edge: 5.6%
• Probability: 58.9%
• College Football Matchup: Old Dominion vs. South Florida (5:00PM ET, Wednesday)

South Florida -2.5 at -114 odds presents a 5.6% edge, with simulations resulting in a probability of 58.9%.

Men's College Basketball: Northern Kentucky -1.5 (-110)

• Edge: 5.3%
• Probability: 57.7%
• Men's College Basketball Matchup: Oakland vs. Northern Kentucky (7:00PM ET, Wednesday)

Our model finds value on Northern Kentucky -1.5 at -110 odds, supported by an edge of 5.3%.

College Football: Delaware ML (+130)

• Edge: 5.3%
• Probability: 48.8%
• College Football Matchup: Louisiana-Lafayette vs. Delaware (8:30PM ET, Wednesday)

Our model has uncovered value on Delaware ML at +130 odds. A 48.8% probability produces a 5.3% edge, making this a strong play for today's college football action.

Men's College Basketball: Texas State +3.5 (-102)

• Edge: 5.3%
• Probability: 55.8%
• Men's College Basketball Matchup: Arkansas State vs. Texas State (8:30PM ET, Wednesday)

A 5.3% edge on a 55.8% probability makes Texas State +3.5 at -102 odds a solid value play in today's Arkansas State vs. Texas State matchup.

Men's College Football: Delaware +3 (-110)

• Edge: 5.1%
• Probability: 57.5%
• Men's College Football Matchup: Louisiana-Lafayette vs. Delaware (8:30PM ET, Wednesday)

Our model projects value on Delaware +3 at -110 odds. A 57.5% probability produces a 5.1% edge, making Delaware the favorable side in Saturday’s men's college football matchup.

Men's College Basketball: Campbell +37.5 (-110)

• Edge: 4.6%
• Probability: 57%
• Men's College Basketball Matchup: Louisiana-Lafayette vs. Delaware (9:00PM ET, Wednesday)

Rounding out our top 10 bets, Campbell +37.5 at -110 odds shows a 57% probability and a 4.6% edge.

Best sports bets today summary: Wednesday, 12/17/2025

As of 4:31AM ET, here are our top bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
St. Francis (PA) vs. Florida (Men's College Basketball)	St. Francis (PA) +45.5	-110 @ BetMGM	9.6%	62%
Louisiana Tech vs. Tulane (Men's College Basketball)	Louisiana Tech +3.5	-108 @ FanDuel	6.5%	58.4%
North Texas vs. Santa Clara (Men's College Basketball)	Santa Clara -11.5	-105 @ BetMGM	6.4%	57.6%
Siena vs. Vermont (Men's College Basketball)	Vermont ML	-118 @ BetMGM	5.9%	60.1%
Old Dominion vs. South Florida (College Football)	South Florida -2.5	-114 @ FanDuel	5.6%	58.9%
Oakland vs. Northern Kentucky (Men's College Basketball)	Northern Kentucky -1.5	-110 @ BetMGM	5.3%	57.7%
Louisiana-Lafayette vs. Delaware (College Football)	Delaware ML	+130 @ DraftKings	5.3%	48.8%
Arkansas State vs. Texas State (Men's College Basketball)	Texas State +3.5	-102 @ BetMGM	5.3%	55.8%
Louisiana-Lafayette vs. Delaware (Men's College Football)	Delaware +3	-110 @ BetMGM	5.1%	57.5%
Campbell vs. Gonzaga (Men's College Basketball)	Campbell +37.5	-110 @ BetMGM	4.6%	57%

List of upcoming sports to bet on now [12/17/2025]

• NCAAF: Old Dominion vs. South Florida (5:00PM ET, Wednesday)
• NCAAM: Northern Iowa vs. Illinois-Chicago (5:00PM ET, Wednesday)
• NCAAM: Creighton vs. Xavier (6:30PM ET, Wednesday)
• NCAAM: St. Francis (PA) vs. Florida (6:30PM ET, Wednesday)
• NCAAM: Mercer vs. UCF (7:00PM ET, Wednesday)
• NCAAM: Vanderbilt vs. Memphis (7:00PM ET, Wednesday)
• NCAAM: UC Santa Barbara vs. Green Bay (7:00PM ET, Wednesday)
• NCAAM: Oakland vs. Northern Kentucky (7:00PM ET, Wednesday)
• NCAAM: Richmond vs. Elon (7:00PM ET, Wednesday)
• NCAAM: Youngstown State vs. Robert Morris (7:00PM ET, Wednesday)

Conclusion

Our best bets are locked and loaded for December 17, 2025, featuring plays such as St. Francis (PA) +45.5 and Louisiana Tech +3.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.