Arizona Cardinals vs. Cincinnati Bengals: Experts release early Week 17 preview [2025]

The Arizona Cardinals and Cincinnati Bengals will meet in Week 17 of the NFL season at Paycor Stadium on Sunday, December 28, 2025, starting at 1:00 PM ET.

Early simulations from Dimers' trusted NFL model favor the Bengals as the most likely winner of this cross-conference clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Cardinals vs. Bengals predictions page.

Arizona vs. Cincinnati early predictions

Leveraging trusted machine learning and analysis, we have simulated the Cardinals vs. Bengals game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Cardinals 31%, Bengals 69%
• Predicted final score: Cardinals 23-29 Bengals
• Spread: Cardinals (+7) 57%, Bengals (-7) 43%
• Total points (53.5): Over 47%, Under 53%

As of December 22, 2025, these Cardinals-Bengals figures and predictions reflect the latest data and insights available.

Cardinals vs. Bengals Week 17 details

The NFL Week 17 matchup between the Bengals and Cardinals at Paycor Stadium is scheduled for December 28, 2025.

• Who: Arizona Cardinals vs. Cincinnati Bengals
• Date: Sunday, December 28, 2025
• Time: 1:00 PM ET/10:00AM PT
• Venue: Paycor Stadium

Cardinals vs. Bengals opening odds

We've researched the best betting odds across America for this Week 17 game, which are listed here:

• Spread: Cardinals +7 (-105), Bengals -7 (-110)
• Moneyline: Cardinals +310, Bengals -350
• Total: Over/Under 53.5 (-110/-108)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 17 highlight the top candidates to score a TD in Cardinals-Bengals in Week 17:

Arizona Cardinals

• Trey McBride: 44.4% probability
• Michael Wilson: 37.5% probability
• Marvin Harrison: 33.0% probability

Cincinnati Bengals

• Tee Higgins: 48.9% probability
• Ja'Marr Chase: 47.9% probability
• Chase Brown: 33.8% probability

Cardinals vs Bengals player props

Michael Carter is projected to lead rushing for the Cardinals, while Chase Brown is expected to pace the Bengals on the ground.

In the receiving game, our projections favor Arizona's Trey McBride and Cincinnati's Ja'Marr Chase as the likely leaders for each team.

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Conclusion

We predict the Bengals, with a 69% win probability, will likely beat the Cardinals in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Cardinals vs. Bengals game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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