Sep 6, 2026
Washington State vs. Washington prediction: Why Washington is favored to win in college football Week 1 [2026]
Read Article Wisconsin vs. Notre Dame prediction: Notre Dame favored to win in college football Week 1 [2026]
Updated: | First published:
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Written by Mac Douglass, Senior Editor
Dimers' simulation model projects a 92.6% win probability for Notre Dame at Lambeau Field.
Notre Dame will take on Wisconsin in Week 1 college football action at Lambeau Field on Sunday, beginning at 7:30 PM ET.
Dimers' advanced college football model projects Notre Dame as the most likely winner in this Wisconsin vs. Notre Dame prediction.
This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.
Wisconsin vs. Notre Dame prediction and odds
Using innovative machine learning and data analysis, we have simulated the result of Wisconsin vs. Notre Dame, forming part of our college football predictions coverage.
Our independent predictive model gives Notre Dame a 92.6% chance of defeating Wisconsin. Our predicted final score has Notre Dame winning 34-13.
According to our model, the bookmakers have got it right, and Wisconsin and Notre Dame each have a 50% chance of covering the spread, while the 46.5-point over/under has a 55.1% chance of going over.
Latest betting odds
We have researched the best college football odds in America for this game, which are listed here:
- Spread: Wisconsin +20.5 (+100) / Notre Dame -20.5 (-110)
- Moneyline: Wisconsin +1100, Notre Dame -1600
- Total: Over/Under 46.5 (-107/-110)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: Wisconsin +20.5 @ +100 via ESPN BET
- Moneyline: Wisconsin @ +1100 via ESPN BET
- Total: Over 46.5 @ -107 via Caesars
According to our college football best bets, the top play to make on this game is Over 46.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & kickoff details
Sunday's college football game between Notre Dame and Wisconsin at Lambeau Field is scheduled to commence at 7:30 PM ET.
- Who: Wisconsin vs. Notre Dame
- Date: Sunday, September 6, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Lambeau Field
College football Week 1 promos
Make the most of Dimers' Wisconsin vs. Notre Dame predictions by exploring the Bet365 Sportsbook offer below:
Conclusion
We predict Notre Dame, with a 92.6% win probability, will likely beat Wisconsin in Sunday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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