Southern California vs. Wisconsin prediction: Why Southern California is favored to win in college football Week 8 [2026]

Using trusted machine learning and data, we have re-simulated the result of Southern California vs. Wisconsin, forming part of our college football predictions coverage.

Our independent predictive model currently gives Southern California a 57.3% chance of defeating Wisconsin. Our predicted final score has Southern California winning 26-23. According to our model, Southern California (-1.5) has a 55.2% chance of covering the spread, while the 50.5-point over/under has a 50.4% chance of staying under.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Southern California -1.5 (-122) / Wisconsin +1.5 (+115)
• Moneyline: Southern California -135, Wisconsin +133
• Total: Over/Under 50.5 (+104/-113)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Southern California -1.5 @ 55¢ via Novig
• Moneyline: Southern California @ 58¢ via Novig
• Total: Over 50.5 @ 49¢ via Novig

According to our college football best bets, the top play to make on this game is Over 50.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Wisconsin and Southern California at Camp Randall Stadium is scheduled to start at 7:30 PM ET.

• Who: Southern California vs. Wisconsin
• Date: Saturday, October 24, 2026
• Time: 7:30 PM ET/4:30 PM PT
• Venue: Camp Randall Stadium

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Conclusion

We predict Southern California, with a 57.3% win probability, will likely beat Wisconsin in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.