Cal Poly vs. San Jose State prediction favors San Jose State to win in college football Week 2 [2026]

San Jose State and Cal Poly will clash in Week 2 college football action at CEFCU Stadium on Saturday, beginning at 9:00 PM ET.

Dimers' advanced college football model projects San Jose State as the most likely winner in this Cal Poly vs. San Jose State prediction.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

Cal Poly vs. San Jose State prediction and odds

Using trusted machine learning and data, we have re-simulated the outcome of Cal Poly vs. San Jose State, forming part of our college football predictions coverage.

Our famous predictive model currently gives San Jose State a 92.0% chance of defeating Cal Poly. Our predicted final score has San Jose State winning 38-19. According to our model, Cal Poly (+21.5) has a 55.2% chance of covering the spread, while the over/under total of 58.5 points has a 51.3% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Cal Poly +21.5 (-106) / San Jose State -21.5 (-107)
• Moneyline: Cal Poly +1400, San Jose State -2000
• Total: Over/Under 58.5 (-105/-108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Cal Poly +21.5 @ -106 via FanDuel
• Moneyline: Cal Poly @ +1400 via BetRivers
• Total: Under 58.5 @ -108 via DraftKings

According to our college football best bets, the top play to make on this game is Cal Poly +21.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between San Jose State and Cal Poly at CEFCU Stadium is scheduled to begin at 9:00 PM ET.

• Who: Cal Poly vs. San Jose State
• Date: Saturday, September 12, 2026
• Time: 9:00 PM ET/6:00PM PT
• Venue: CEFCU Stadium

College football Week 2 promos

Make the most of Dimers' Cal Poly vs. San Jose State predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict San Jose State, with a 92.0% win probability, will likely beat Cal Poly in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.