Bills vs. Patriots Preview and Prediction

Bills vs. Patriots: Detailed Breakdown

Matchup Overview

• Teams: Bills vs. Patriots
• Date: Sunday, December 14, 2025
• Time: 1:00 PM ET
• Venue: Gillette Stadium
• NFL stats, rosters and injury reports

Current Betting Odds

• Spread: Bills favored at -4.5
• Total (Over/Under): 48.5
• Moneyline Odds: Bills -102, Patriots +165

Dimers' Win Probabilities

• Bills: 56%
• Patriots: 44%

Dimers' predictive NFL model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Projected Final Score

Our predicted final score for this NFL matchup is Bills 25-23 Patriots.

This prediction is based on each team's average score and player stats following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Bills a win probability of 56%, while the Patriots have a win probability of 44%.

Summary

The Bills face off against the Patriots in the NFL at Gillette Stadium on Sunday, December 14, 2025. On this page, you'll find our preview, analysis and data-driven projections for the game.

Our Bills vs. Patriots predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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