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Old Dominion vs. South Florida Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Old Dominion vs. South Florida NCAAF game on December 17, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Old Dominion
Predicted score
24
:
29
Dec 17, 10PM Camping World Stadium
South Florida
Dec 17, 10PM Camping World Stadium
Game PredictionsPre-Game
Dimers Pro Best Bets
Pre-Game Probabilities Last Updated: 12:41AM, Dec 11
Spread
Over / Under
Moneyline
Old Dominion ODU
South Florida -3.5
Spread
48%
53%
South Florida USF

Game Prediction Article

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Old Dominion vs. South Florida: Detailed Breakdown

Matchup Overview

  • Teams: Old Dominion vs. South Florida
  • Date: Wednesday, December 17, 2025
  • Time: 5:00 PM ET
  • Venue: Camping World Stadium

Current Betting Odds

  • Spread: South Florida favored at -3.5
  • Total (Over/Under): 53.5
  • Moneyline Odds: Old Dominion +146, South Florida -162

Dimers' Win Probabilities

  • Old Dominion: 37%
  • South Florida: 63%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Old Dominion 24-29 South Florida.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Old Dominion a win probability of 37%, while South Florida has a win probability of 63%.

Summary

According to our analysis, South Florida is more likely to beat Old Dominion in CFB action at Camping World Stadium on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Old Dominion vs. South Florida predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.

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