Indiana vs. Ohio State Prediction, Picks and Odds

Indiana vs. Ohio State: Detailed Breakdown

Matchup Overview

• Teams: Indiana vs. Ohio State
• Date: Saturday, December 6, 2025
• Time: 8:00 PM ET
• Venue: Lucas Oil Stadium

Current Betting Odds

• Spread: Ohio State favored at -3.5
• Total (Over/Under): 46.5
• Moneyline Odds: Indiana +155, Ohio State -166

Dimers' Win Probabilities

• Indiana: 36%
• Ohio State: 64%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Indiana 21-26 Ohio State.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Indiana a win probability of 36%, while Ohio State has a win probability of 64%.

Summary

According to our analysis, Ohio State is more likely to beat Indiana in CFB action at Lucas Oil Stadium on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Indiana vs. Ohio State predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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