Matteo Berrettini vs. Mariano Navone prediction, odds, picks for US Open 2026

Using trusted machine learning and data, we have simulated the result of Wednesday's Berrettini-Navone men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model currently gives Berrettini a 67% chance of winning against Navone in the US Open 2026.

Matteo Berrettini vs. Mariano Navone odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Mariano Navone +158, Matteo Berrettini -192

All odds are correct at the time of publication and are subject to change.

Berrettini vs. Navone picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Berrettini @ -192 via DraftKings
• First Set: Navone @ -140 via DraftKings

According to our tennis best bets, the top play to make on this match is over 39.5 total games.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Berrettini vs. Navone updates and essential details

The US Open 2026 match between Matteo Berrettini and Mariano Navone is scheduled to start on Wednesday at 11:00 AM ET.

• Who: Matteo Berrettini vs. Mariano Navone
• Date: Wednesday, September 2, 2026
• Approx. Time: 11:00 AM ET/8:00AM PT
• Tournament: US Open Men's Singles 2026
• Round: Second round

All dates and times in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Matteo Berrettini, with a 67% win probability, will likely beat Mariano Navone at the US Open 2026.

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