Alexei Popyrin vs. Alejandro Tabilo prediction, odds, picks for US Open 2026

Alexei Popyrin will face Alejandro Tabilo in the second round of the US Open Men's Singles 2026 on Thursday.

Dimers' advanced tennis model projects Alejandro Tabilo as the most likely winner in this Popyrin vs. Tabilo prediction.

This article offers an expanded analysis of Thursday's match, including best bets and picks.

Popyrin vs. Tabilo prediction and odds

Using innovative machine learning and data, we have simulated the result of Thursday's Popyrin-Tabilo men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model gives Tabilo a 58% chance of defeating Popyrin in the US Open 2026.

Additionally, Tabilo has a 54% chance of winning the first set. The simulations also show Popyrin (+2.5) has a 53% chance of covering the games spread, while the under 40.5 games has a 56% chance of hitting, according to our model.

Latest betting odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Alejandro Tabilo -150, Alexei Popyrin +142
• First Set: Popyrin +110, Tabilo -139

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Popyrin @ +142 via DraftKings
• First Set: Tabilo @ -120 via DraftKings

According to our tennis best bets, the top play to make on this match is Alexei Popyrin to win.

Although Popyrin is less than likely to win, he provides the best value at the current available odds.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The US Open 2026 match between Alexei Popyrin and Alejandro Tabilo is scheduled to start on Thursday at 2:20 PM ET.

• Who: Alexei Popyrin vs. Alejandro Tabilo
• Date: Thursday, September 3, 2026
• Approx. Time: 2:20 PM ET/11:20AM PT
• Tournament: US Open Men's Singles 2026
• Round: Second round

All dates and times in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Alejandro Tabilo, with a 58% win probability, will likely beat Alexei Popyrin at the US Open 2026.

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