Jaguars vs. Broncos: NFL Week 2 Prediction, Picks & Odds

Dimers' Jaguars vs. Broncos prediction for Sunday, September 20, 2026. Win probabilities, projected final score, current odds, and picks from our NFL machine learning models.
NFL
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NFL
Jaguars
Predicted score
21
:
24
Empower Field at Mile High
Broncos
Empower Field at Mile High
Pre-Game Probabilities Last Update:

Spread

Jaguars +3.0
Spread
  • Jaguars
    54.7%
    CaesarsCaesars
  • Broncos
    45.3%
    BetRiversBetRivers

Jaguars vs. Broncos: Detailed Breakdown

Matchup overview: NFL Week 2

  • Teams: Jacksonville Jaguars vs. Denver Broncos
  • Date: Sunday, September 20, 2026
  • Time: 4:05PM ET
  • Venue: Empower Field at Mile High

Current betting odds

  • Spread: Jaguars (+3, -109), Broncos (-3, -109)
  • Moneyline: Jaguars +133, Broncos -148
  • Total (Over/Under): 43.5 points (-110/-110)

Dimers’ win probabilities

  • Jaguars: 41.2%
  • Broncos: 58.8%

These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this NFL matchup is Jaguars 21-23 Broncos.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models.

Our Prediction: Who Wins?

The numbers give the Jaguars a win probability of 41.2%, while the Broncos have a win probability of 58.8%.

Summary

The Jaguars face off against the Broncos in the NFL at Empower Field at Mile High on Sunday, September 20, 2026.

Our Jaguars vs. Broncos predictions, built on real-time data and matchup-specific modeling, help guide your decisions.. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.