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Read Article Ignacio Buse vs. Adrian Mannarino prediction, odds, picks for ATP Madrid Open 2026
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Buse vs Mannarino predictions for ATP Madrid Open.
Ignacio Buse will face Adrian Mannarino in the round of 128 at the ATP Madrid event on Wednesday.
Based on updated simulations, Dimers' proven tennis model projects Ignacio Buse as the most likely winner of the Buse vs. Mannarino match.
This article offers further insights into Wednesday's match, including best bets and picks.
Buse vs. Mannarino prediction: Who will win and advance to the second round?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's Buse-Mannarino men's singles match, forming part of our tennis predictions coverage.
Our leading predictive model currently gives Buse an 84% chance of defeating Mannarino at the ATP Madrid Open tournament.
Additionally, Buse has a 79% chance of winning the first set. The simulations also show Buse (-4.5) has a 53% chance of covering the games spread, while the under 20.5 games has a 51% chance of hitting, according to our model.
Ignacio Buse vs. Adrian Mannarino odds
We have researched the most up-to-date betting odds in America for this match, which are listed here:
| Bet Type | Buse | Mannarino |
|---|---|---|
| Moneyline | -641 | +500 |
| First Set | -455 | +333 |
| Game Spread | -4.5 (-132) | +4.5 (-102) |
| Total Games | o20.5 (-115) | u20.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Buse vs. Mannarino picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Mannarino | +500 |
| First Set | Mannarino | -110 |
According to our tennis best bets, the top play to make on this match is over 20.5 total games.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Buse vs. Mannarino updates and essential details
The ATP Madrid Open match between Ignacio Buse and Adrian Mannarino is scheduled to begin on Wednesday at 6:10 AM ET.
- Who: Ignacio Buse vs. Adrian Mannarino
- Date: Wednesday, April 22, 2026
- Approx. Time: 6:10 AM ET/3:10AM PT
- Tournament: ATP Madrid, Spain Men's Singles 2026
- Round: Round of 128
All dates and times in this article are United States Eastern Time unless otherwise stated.
Conclusion
We predict Ignacio Buse, with an 84% win probability, will likely beat Adrian Mannarino at the ATP Madrid Open tournament.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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