Club Leon vs. San Luis prediction, odds, Liga MX picks [9/14/2026]

Club Leon and Atletico San Luis will meet in Liga MX on Monday, with kickoff at 9:00 PM ET.

Dimers' advanced Liga MX model projects Club Leon as the most likely winner in this Club Leon vs. Atletico San Luis prediction.

This article offers further insights into Monday's match, including best bets and picks.

Club Leon vs. Atletico San Luis prediction and odds

Using innovative machine learning and data, we have re-simulated the outcome of Monday's Liga MX matchup between Club Leon and Atletico San Luis, forming part of our Liga MX predictions coverage.

Our famous predictive model suggests a 50.8% chance of Club Leon winning, a 26.0% chance for Atletico San Luis, and a 23.2% chance of a draw. Additionally, the over/under total of 2.5 goals has a 58.0% chance of going over., with a 58.8% chance that both teams score.

Latest betting odds

We have researched the best Liga MX odds in America for this game, which are listed here:

• Moneyline: Atletico San Luis +270, Club Leon -110
• Total Goals: Over/Under 2.5 (-162/+134)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: San Luis @ +270 via FanDuel
• Total Goals: Under 2.5 @ +134 via FanDuel

According to our best Liga MX bets, the top play to make on this game is Under 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score and BTTS projections

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

• Club Leon 1-1 San Luis (10.7% probability)
• Club Leon 2-1 San Luis (9.6%)
• Club Leon 1-0 San Luis (8.8%)

When it comes to the both teams to score (BTTS) market, we project a 58.8% chance of both sides finding the net and a 41.2% chance that at least one doesn’t.

These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score can differ from our predicted winner.

Game info & kickoff details

Monday's Liga MX game between Club Leon and Atletico San Luis is scheduled to start at 9:00 PM ET.

• Who: Club Leon vs. Atletico San Luis
• Date: Monday, September 14, 2026
• Time: 9:00 PM ET/6:00PM PT

Conclusion

According to our computer model, Club Leon has a 50.8% win probability on Monday, Atletico San Luis has a 26.0% win probability, and there is a 23.2% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary Liga MX prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.