Old Dominion vs. Virginia Tech prediction favors Virginia Tech to win in college football Week 2 [2026]

Virginia Tech will square off with Old Dominion in Week 2 college football action at Lane Stadium on Saturday, starting at 12:00 PM ET.

Dimers' advanced college football model projects Virginia Tech as the most likely winner in this Old Dominion vs. Virginia Tech prediction.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

Old Dominion vs. Virginia Tech prediction and odds

Using powerful machine learning and statistical analysis, we have re-simulated the outcome of Old Dominion vs. Virginia Tech, forming part of our college football predictions coverage.

Our famous predictive model gives Virginia Tech a 91.5% chance of beating Old Dominion. Our predicted final score has Virginia Tech winning 34-14. According to our model, Virginia Tech (-17.5) has a 54.2% chance of covering the spread, while the over/under total of 47.5 points has a 53.6% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Old Dominion +17.5 (-105) / Virginia Tech -17.5 (-115)
• Moneyline: Old Dominion +810, Virginia Tech -1000
• Total: Over/Under 47.5 (-110/-105)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Virginia Tech -17.5 @ -115 via bet365
• Moneyline: Virginia Tech @ -1000 via DraftKings
• Total: Over 47.5 @ -110 via FanDuel

According to our college football best bets, the top play to make on this game is Over 47.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Virginia Tech and Old Dominion at Lane Stadium is scheduled to start at 12:00 PM ET.

• Who: Old Dominion vs. Virginia Tech
• Date: Saturday, September 12, 2026
• Time: 12:00 PM ET/9:00AM PT
• Venue: Lane Stadium

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Conclusion

We predict Virginia Tech, with a 91.5% win probability, will likely beat Old Dominion in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.