Sep 5, 2026
Furman vs. Tennessee prediction: Why Tennessee is favored to win in college football Week 1 [2026]
Read Article Ohio vs. Nebraska prediction: Nebraska favored to win in college football Week 1 [2026]
Updated: | First published:
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Written by Mac Douglass, Senior Editor
Dimers' simulation model projects a 95.9% win probability for Nebraska at Memorial Stadium (Lincoln.
Nebraska will take on Ohio in Week 1 college football action at Memorial Stadium on Saturday, beginning at 12:00 PM ET.
Dimers' proven college football model projects Nebraska as the most likely winner in this Ohio vs. Nebraska prediction.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.
Ohio vs. Nebraska prediction and odds
Using innovative machine learning and statistical analysis, we have simulated the result of Ohio vs. Nebraska, forming part of our college football predictions coverage.
Our independent predictive model currently gives Nebraska a 95.9% chance of beating Ohio. Our predicted final score has Nebraska winning 35-11.
According to our model, Ohio (+24.5) has a 54.0% chance of covering the spread, while the over/under total of 47.5 points has a 52.6% chance of staying under.
Latest betting odds
We have sourced the best college football odds in America for this game, which are listed here:
- Spread: Ohio +24.5 (-115) / Nebraska -24.5 (-104)
- Moneyline: Ohio +1600, Nebraska -2500
- Total: Over/Under 47.5 (-110/-110)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: Ohio +24.5 @ -115 via BetMGM
- Moneyline: Nebraska @ -2500 via bet365
- Total: Under 47.5 @ -110 via BetMGM
According to our college football best bets, the top play to make on this game is Ohio +24.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & kickoff details
Saturday's college football game between Nebraska and Ohio at Memorial Stadium is scheduled to commence at 12:00 PM ET.
- Who: Ohio vs. Nebraska
- Date: Saturday, September 5, 2026
- Time: 12:00 PM ET/9:00AM PT
- Venue: Memorial Stadium
College football Week 1 promos
Make the most of Dimers' Ohio vs. Nebraska predictions by exploring the Bet365 Sportsbook offer below:
Conclusion
We predict Nebraska, with a 95.9% win probability, will likely beat Ohio in Saturday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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