Holy Cross vs. Colgate prediction: Why Colgate is favored to win in college football Week 1 [2026]
Dimers' simulation model projects a 64.9% win probability for Colgate at Crown Field at Andy Kerr Stadium.

Colgate and Holy Cross will clash in Week 1 college football action at Crown Field at Andy Kerr Stadium on Saturday, starting at 1:00 PM ET.
Dimers' advanced college football model projects Colgate as the most likely winner in this Holy Cross vs. Colgate prediction.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.
Holy Cross vs. Colgate prediction and odds
Our leading predictive model currently gives Colgate a 64.9% chance of beating Holy Cross. Our predicted final score has Colgate winning 26-21.
According to our model, Colgate (-4.5) has a 51.9% chance of covering the spread, while the over/under total of 47 points has a 51.3% chance of going over.
Latest betting odds
We have researched the best college football odds in America for this game, which are listed here:
- Spread: Holy Cross +4.5 (-110) / Colgate -4.5 (-110)
- Moneyline: Holy Cross +155, Colgate -181
- Total: Over/Under 47 (-111/-111)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: Colgate -4.5 @ -110 via bet365
- Moneyline: Colgate @ -181 via DraftKings
- Total: Over 47 @ -111 via Fanatics
According to our college football best bets, the top play to make on this game is Colgate to win.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & kickoff details
Saturday's college football game between Colgate and Holy Cross at Crown Field at Andy Kerr Stadium is scheduled to begin at 1:00 PM ET.
- Who: Holy Cross vs. Colgate
- Date: Saturday, September 5, 2026
- Time: 1:00 PM ET/10:00AM PT
- Venue: Crown Field at Andy Kerr Stadium
College football Week 1 promos
Make the most of Dimers' Holy Cross vs. Colgate predictions by exploring the Underdog Fantasy offfer below
Conclusion
We predict Colgate, with a 64.9% win probability, will likely beat Holy Cross in Saturday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.




