Milwaukee vs. Santa Clara prediction, odds, pick for Nov. 4, 2026

Santa Clara is favored to beat Milwaukee at Leavey Center on Wednesday (10:00 PM ET), according to Dimers' men's college basketball model.

Our Milwaukee vs. Santa Clara prediction gives Santa Clara a 93.4% chance of winning, while the latest odds suggest the best betting value is on the under 160.5 points.

Milwaukee vs. Santa Clara key predictions

• Predicted score: Santa Clara 87-69 Milwaukee
• Santa Clara win probability: 93.4%
• Milwaukee win probability: 6.6%
• Santa Clara -16.5 spread: 53.8% cover probability
• Under 160.5 points: 52.9% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Milwaukee vs. Santa Clara odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• Milwaukee moneyline: +1160 (FanDuel)
• Santa Clara moneyline: -2000 (BetRivers)
• Milwaukee +16.5: -102 (DraftKings)
• Santa Clara -16.5: -110 (BetRivers)
• Over 160.5 points: -105 (BetMGM)
• Under 160.5 points: -105 (FanDuel)

Odds are subject to change and may vary by location.

Milwaukee vs. Santa Clara pick: Under 160.5 (-105)

Our model makes Santa Clara the likelier winner, but our best value bet is the under 160.5 total points at -105 on FanDuel.

Those odds give the under an implied probability of 51.2%, while our model puts it at 52.9%.

That's a 1.7% edge, the largest across the moneyline, spread, and total points markets for this game.

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Milwaukee vs. Santa Clara game details

• Matchup: Milwaukee Panthers vs. Santa Clara Broncos
• Date: Wednesday, November 4, 2026
• Time: 10:00 PM ET
• Venue: Leavey Center

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.