Duke vs. Syracuse Prediction, Picks and Odds

Duke vs. Syracuse: Detailed Breakdown

Matchup Overview

• Teams: Duke vs. Syracuse
• Date: Sunday, December 28, 2025
• Time: 4:00 PM ET
• Venue: JMA Wireless Dome

Current Betting Odds

• Spread: Duke favored at -8.5
• Total (Over/Under): 133.5
• Moneyline Odds: Duke -395, Syracuse +310

Dimers' Win Probabilities

• Duke: 94%
• Syracuse: 6%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this Women's College Basketball matchup is Duke 71-56 Syracuse.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Duke a win probability of 94%, while Syracuse has a win probability of 6%.

Summary

According to our analysis, Duke is more likely to beat Syracuse in CBB action at JMA Wireless Dome on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Duke vs. Syracuse predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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