Anastasia Potapova vs. Amanda Anisimova prediction, odds, picks for US Open 2026

Anastasia Potapova will take on Amanda Anisimova in the third round of the US Open Women's Singles 2026 on Saturday.

Dimers' proven tennis model projects Amanda Anisimova as the most likely winner in this Potapova vs. Anisimova prediction.

This article offers an expanded analysis of Saturday's match, including best bets and picks.

Potapova vs. Anisimova prediction and odds

Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's Potapova-Anisimova women's singles match, forming part of our tennis predictions coverage.

Our famous predictive model gives Anisimova an 82% chance of winning against Potapova in the US Open 2026.

Additionally, Anisimova has a 76% chance of winning the first set. The simulations also show Potapova (+5.5) has a 53% chance of covering the games spread, while the under 20.5 games has a 56% chance of hitting, according to our model.

Latest betting odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Amanda Anisimova -588, Anastasia Potapova +460
• First Set: Potapova +300, Anisimova -400

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Potapova @ +460 via DraftKings
• First Set: Anisimova @ -140 via DraftKings

According to our tennis best bets, the top play to make on this match is Anastasia Potapova to win.

Although Potapova is less than likely to win, she provides the best value at the current available odds.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The US Open 2026 match between Anastasia Potapova and Amanda Anisimova is scheduled to begin on Saturday at 11:00 AM ET.

• Who: Anastasia Potapova vs. Amanda Anisimova
• Date: Saturday, September 5, 2026
• Approx. Time: 11:00 AM ET/8:00AM PT
• Tournament: US Open Women's Singles 2026
• Round: Third round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Amanda Anisimova, with an 82% win probability, will likely beat Anastasia Potapova at the US Open 2026.

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