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Wisconsin vs. Purdue CFB Prediction and Odds - September 22, 2023

Purdue and Wisconsin meet in College Football action at Ross-Ade Stadium on Friday, starting at 7:00PM ET.

Dimers' top betting picks for Wisconsin vs. Purdue, plus game predictions and best odds, are detailed below.

This Wisconsin vs. Purdue betting preview is presented by Bet365, which has a tasty Bet $1, Get $365 in Bonus Bets offer for new customers.

Who Will Win: Wisconsin vs. Purdue

Using trusted machine learning and data, Dimers.com has simulated Wisconsin vs. Purdue 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives Wisconsin a 66% chance of defeating Purdue.

More: Wisconsin vs. Purdue Simulated 10,000 Times

Wisconsin vs. Purdue Odds

  • Spread: Purdue +6 (-110), Wisconsin -6 (-110)
  • Moneyline: Purdue +205, Wisconsin -245
  • Total: Over/Under 54 (-110/-110)

Purdue is listed as the +6 underdog against Wisconsin, with -110 at PointsBet the best odds currently available.

For the favored Wisconsin (-6) to cover the spread, PointsBet also has the best odds currently on offer at -110.

DraftKings Sportsbook currently has the best moneyline odds for Purdue at +205, which means you can bet $100 to profit $205, earning a total payout of $305, if it wins.

Elsewhere, PointsBet currently has the best moneyline odds for Wisconsin at -245, where you can risk $245 to win $100, for a total payout of $345, if it comes out on top.

The Over/Under sits at 54 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all of the online sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Purdue (+6) has a 51% chance of covering the spread, while the 54-point Over/Under has a 56% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets: Wisconsin vs. Purdue


Our best bets are based on world-class modeling and wagering intelligence to serve you the best possible plays 24/7/365.

While Wisconsin is more likely to win the game, according to DimersBOT, taking Purdue moneyline is the best option because of the 1.7% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is one of the keys to achieving long-term profitability as a bettor.

Wisconsin vs. Purdue Prediction

Dimers.com's predicted final score for Wisconsin vs. Purdue at Ross-Ade Stadium this Friday has Wisconsin winning 28-22.

Click or tap on See Matchup to find out more.


Dimers has full betting coverage of this week's Wisconsin-Purdue game, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this page for any changes to our betting analysis before Wisconsin vs. Purdue on Friday September 22, 2023.

Another great way to make the most of this Wisconsin vs. Purdue game is by using the latest DraftKings promo, where a bet as small as $5 guarantees you $200 in bonus bets.

Wisconsin vs. Purdue 2023

Friday's matchup between Purdue and Wisconsin in College Football at Ross-Ade Stadium is scheduled to start at 7:00PM ET.

  • Who: Wisconsin vs. Purdue
  • Date: Friday September 22, 2023
  • Time: 7:00PM ET / 4:00PM PT
  • Venue: Ross-Ade Stadium

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Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Wisconsin vs. Purdue picks can help you make informed decisions, it's important that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More CFB Analysis Like This?

To get more NCAA Football betting previews like you've just read for Wisconsin vs. Purdue, all you've gotta do is visit our College Football Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the most comprehensive CFB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – check out our College Football picks and predictions.

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the top odds available every day of the CFB season.


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