MLB- More Betting
White Sox vs. Guardians Prediction and Odds - Jul 11, 2022

The Cleveland Guardians face the Chicago White Sox in MLB action at Progressive Field on Monday, commencing at 7:10PM ET.
The Guardians will have Cal Quantrill (4-5, 3.86 ERA) start, while the White Sox are going with Lance Lynn (1-1, 5.33 ERA).
Dimers' free betting picks for White Sox vs. Guardians, plus game predictions and betting odds, are featured in this article.
Who will win White Sox vs. Guardians?
Based on state-of-the-art machine learning and data, Dimers.com has simulated Monday's White Sox-Guardians MLB matchup 10,000 times.
Dimers' famous predictive analytics model, DimersBOT, currently gives the White Sox a 51% chance of beating the Guardians.
More: Free Betting Analysis for White Sox vs. Guardians
White Sox vs. Guardians Game Odds
- Run Line: Guardians +1.5 (-160), White Sox -1.5 (+146)
- Moneyline: Guardians -105, White Sox -110
- Total: Over/Under 9 (-106/+100)
Run Line, Moneyline and Over/Under
The Guardians are +1.5 underdogs against the White Sox, with -160 at BetMGM the best odds currently available.
For the favored White Sox (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +146.
In a sign of how close this game is expected to be, both the Guardians and White Sox are currently at minus-money betting odds on the moneyline.
PointsBet currently has the best moneyline odds for the Guardians at -105, which means you can risk $105 to win $100, for a total payout of $205, if they get the W.
Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the White Sox at -110, where you can risk $110 to win $100, for a total payout of $210, if they come out on top.
The Over/Under for total runs scored sits at 9 with FanDuel Sportsbook, which currently has the best odds for the Over at -106, while BetMGM currently has the best odds for the Under at +100.
As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.
According to DimersBOT, the Guardians (+1.5) are a 62% chance of covering the run line, while the Over/Under total of 9 runs is a 53% chance of going Over.
More: Track Your Bets via Dimers' Bet Center
Best Bets for White Sox vs. Guardians
- Run Line: Guardians +1.5 @ -160 via BetMGM (62% probability)
- Moneyline: Guardians @ -105 via PointsBet
- Total: Over 9 @ -106 via FanDuel Sportsbook (53% probability)
Dimers' best bets are based on world-class simulations and wagering expertise to help you make smarter decisions with your state's legal sportsbooks.
While the White Sox are more likely to win the game, according to DimersBOT, taking the Guardians moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.
Taking advantage of the edges seen on Dimers.com is one of the keys to achieving long-term profitability as a sports bettor.
White Sox vs. Guardians Prediction
Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Cleveland, and click or tap on See Matchup for more.
Dimers has full betting coverage of Monday's White Sox-Guardians matchup, including pregame predictions, computer picks, and live updates.
Don't forget, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis before White Sox vs. Guardians on Monday July 11, 2022.
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Note: When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may receive a referral fee.
White Sox vs. Guardians 2022 Game Info
Monday's matchup between the Guardians and White Sox at Progressive Field is scheduled to begin at 7:10PM ET.
- Who: Cleveland Guardians vs. Chicago White Sox
- Date: Monday July 11, 2022
- Time: 7:10PM ET / 4:10PM PT
- Venue: Progressive Field
Looking to join an online sportsbook and start betting on MLB today? We've reviewed the best available sign-up offers in each and every legal betting state.
What other MLB games are on today?
Now you've got the 411 on White Sox vs. Guardians, see the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, plus our best bets for every single MLB matchup.
Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!
Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.
