Syracuse vs. Clemson CBB Prediction and Odds - Feb 22, 2023

Clemson faces Syracuse in College Basketball action at Littlejohn Coliseum on Wednesday, commencing at 7:00PM ET.

Dimers' top betting picks for Syracuse vs. Clemson, plus game predictions and best odds, are featured below.

Who will win Syracuse vs. Clemson?

Based on high-tech computer power and data, Dimers.com has simulated Wednesday's Syracuse-Clemson College Basketball matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives Clemson a 64% chance of beating Syracuse.

More: Syracuse vs. Clemson Simulated 10,000 Times

Syracuse vs. Clemson Current Odds

• Spread: Clemson -5 (-110), Syracuse +5 (-110)
• Moneyline: Clemson -200, Syracuse +175
• Total: Over/Under 145.5 (-110/-110)

Point Spread, Moneyline and Over/Under

Clemson is the -5 favorite against Syracuse, with -110 at DraftKings Sportsbook the best odds currently available.

For the underdog Syracuse (+5) to cover the spread, DraftKings Sportsbook also has the best odds currently on offer at -110.

PointsBet currently has the best moneyline odds for Clemson at -200, which means you can risk $200 to win $100, for a total payout of $300, if it gets the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for Syracuse at +175, where you can bet $100 to profit $175, earning a total payout of $275, if it wins.

The Over/Under for total points scored sits at 145.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all of the online sportsbooks that are available in your state for the best College Basketball odds and lines.

According to DimersBOT, Syracuse (+5) is a 58% chance of covering the spread, while the 145.5-point Over/Under is considered an equal 50-50 chance of hitting.

More: Best Prop Bets Today

Best Bets for Syracuse vs. Clemson

• Spread: Syracuse +5 @ -110 via DraftKings Sportsbook (58% probability) 🔥
• Moneyline: Syracuse @ +175 via DraftKings Sportsbook (0.1% edge)
• Total: Under 145.5 @ -110 via PointsBet (50% probability)

Any time you see a 🔥, that means it's one of our best free picks today across all sports.

Our best bets are based on detailed simulations and betting intelligence to serve you the best possible plays every time.

While Clemson is more likely to win the game, according to DimersBOT, betting on Syracuse moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers is crucial to achieving long-term profitability.

Syracuse vs. Clemson Prediction

Dimers.com's predicted final score for Syracuse vs. Clemson at Littlejohn Coliseum this Wednesday has Clemson winning 74-71.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Syracuse-Clemson matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates regularly, so refresh this article for the latest betting insights ahead of Syracuse vs. Clemson on Wednesday February 22, 2023.

Syracuse vs. Clemson 2023 CBB Game Info

Wednesday's matchup between Clemson and Syracuse in College Basketball at Littlejohn Coliseum is scheduled to start at 7:00PM ET.

• Who: Syracuse vs. Clemson
• Date: Wednesday February 22, 2023
• Time: 7:00PM ET / 4:00PM PT
• Venue: Littlejohn Coliseum

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Want more CBB analysis like this?

To get more NCAA Basketball betting previews like you've just read for Syracuse vs. Clemson, all you've gotta do is visit Dimers' College Basketball Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the most comprehensive CBB betting previews available. We do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Finally, Dimers' NCAA Basketball Futures page is our in-house approach to revealing who will win March Madness 2022, with our data-led probabilities paired with the best odds to win the NCAA Tournament.