St. Louis Cardinals vs. Chicago Cubs: Model Emphatically Predicts Cardinals to Cover the Run Line After New Data Released for Sunday's MLB Game [6/16/2024]

St. Louis Cardinals vs. Chicago Cubs: Model Emphatically Predicts Cardinals to Cover the Run Line After New Data Released for Sunday's MLB Game [6/16/2024]

The Chicago Cubs will take on the St. Louis Cardinals in MLB action at Wrigley Field on Sunday, commencing at 1:05PM ET.

Jameson Taillon (3-2, 3.09 ERA) will get the ball for the Cubs, while the Cardinals have opted for Miles Mikolas (4-6, 4.85 ERA).

Based on updated simulations,’s predictive MLB model (see Dimers Pro for full access) has selected the CHI Cubs Cubs as the most likely winner of the game.

“We have simulated the outcome of Sunday's Cardinals-Cubs game 10,000 times using the latest data,” said data analyst Greg Butyn. “Incorporating the most recent updates along with thousands of other variables, we estimate the Cubs' chance of winning at 54%, with the Cardinals at 46%.”

Cardinals vs. Cubs Game-Day Updates and Essential Details

Sunday's MLB matchup between the Cubs and Cardinals at Wrigley Field is scheduled to commence at 1:05PM ET.'s in-depth preview of Sunday's Cardinals vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any the Cubs vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Cardinals vs. Cubs Prediction: Who Will Win, Cover the Run Line

We have used innovative machine learning and statistics to simulate the outcome of Sunday's MLB game between the Cardinals and Cubs 10,000 times, in keeping with our coverage of MLB picks.

Our independent predictive analytics model gives the Cubs a 54% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 63% chance of covering the run line, while the 10.5-run over/under has a 55% chance of going under.


Cardinals vs. Cubs Odds [6/16/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Cardinals Cubs
Run Line +1.5 (-160) -1.5 (+146)
Moneyline +110 -130
Total o10.5 (-102) u10.5 (-110)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. Cubs Picks

The strongest edge our model has found in this Cardinals vs. Cubs matchup is on the run line. Our expert predictions, matched against the best odds, reveal MLB best bets in each major market, every day of the season.

Full access to our picks is available via Dimers Pro.

Plus, gain access to all of today's bets, expert analysis, real-time updates, and exclusive insights, including unlimited best bets, props, trends, and customizable parlays.

Calling Our Shot: Best Bets

Calling Our Shot produces daily MLB betting content, including the best bets featured below.


We predict the Cubs, with a 54% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

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