Southern Illinois vs. Northwestern CFB Prediction and Odds - Sep 17, 2022

Last updated: Dec 21, 2023, 1:31PM | Published: Sep 17, 2022, 2:21AM

Northwestern takes on Southern Illinois in College Football action at Ryan Field on Saturday, starting at 12:00PM ET.

Dimers' free betting picks for Southern Illinois vs. Northwestern, plus game predictions and best odds, are featured below.

Today's Southern Illinois vs. Northwestern betting preview is proudly sponsored by DraftKings Sportsbook, which has an outstanding Bet $5, Win $200 promo for new customers.

Who will win Southern Illinois vs. Northwestern?

Using cutting-edge computer power and data, Dimers.com has simulated Southern Illinois vs. Northwestern 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives Northwestern an 81% chance of defeating Southern Illinois.

More: Full Betting Guide for Southern Illinois vs. Northwestern

Southern Illinois vs. Northwestern Current Odds

Spread: Northwestern -13.5 (-110), Southern Illinois +13.5 (-110)
Moneyline: Northwestern -580, Southern Illinois +460
Total: Over/Under 58 (-110/-110)

Point Spread, Moneyline and Over/Under

Northwestern is the -13.5 favorite versus Southern Illinois, with -110 at DraftKings Sportsbook the best odds currently available.

For the underdog Southern Illinois (+13.5) to cover the spread, DraftKings Sportsbook also has the best odds currently on the market at -110.

FanDuel Sportsbook currently has the best moneyline odds for Northwestern at -580, which means you can risk $580 to win $100, for a total payout of $680, if it gets the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for Southern Illinois at +460, where you can bet $100 to profit $460, earning a total payout of $560, if it wins.

The Over/Under for total points scored sits at 58 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all of the legal sportbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Northwestern (-13.5) is a 52% chance of covering the spread, while the Over/Under total of 58 points is a 53% chance of going Under.

More: Live Win Probabilities for All Major College Sports

Best Bets for Southern Illinois vs. Northwestern

Spread: Northwestern -13.5 @ -110 via DraftKings Sportsbook (52% probability)
Moneyline: Southern Illinois @ +460 via DraftKings Sportsbook (1.0% edge)
Total: Under 58 @ -110 via DraftKings Sportsbook (53% probability)

Dimers' best bets are based on complex modeling and wagering intelligence to serve you the best possible plays 24/7.

While Northwestern is more likely to win the game, according to DimersBOT, betting on Southern Illinois moneyline is the best option due to the 1.0% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability.

Southern Illinois vs. Northwestern Prediction

Dimers.com's predicted final score for Southern Illinois vs. Northwestern at Ryan Field this Saturday has Northwestern winning 35-21.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Southern Illinois-Northwestern matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep an eye on this article for any changes to our betting analysis ahead of Southern Illinois vs. Northwestern on Saturday September 17, 2022.

Southern Illinois vs. Northwestern 2022 CFB Game Info

Saturday's matchup between Northwestern and Southern Illinois in College Football at Ryan Field is scheduled to start at 12:00PM ET.

Who: Southern Illinois vs. Northwestern
Date: Saturday September 17, 2022
Time: 12:00PM ET / 9:00AM PT
Venue: Ryan Field

Want to join an online sportsbook and start betting on College Football? We've reviewed the best available welcome offers in each legal betting state.

What other CFB games are on this week?

Southern Illinois and Northwestern aren't the only two NCAA Football teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every CFB game via our College Football Predictions section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!

Kevin Hansen

Senior Sports Analyst

Kevin Hansen has a track record of delivering high-quality content. He writes about all sports, but his favorites are the NFL, NBA, MLB, and NHL. Kevin enjoys crunching the numbers and using data-driven insights to take on the sportsbooks. The majority of Kevin's time is spent writing about sports betting. His love for data and analytics drove him into the world of sports betting. Finding an edge in sports betting can take a long time, but Kevin believes it is well worth the effort. Kevin is just as passionate about sports as you are, and he empowers fellow bettors to become more educated through simple, actionable betting tips. It can be difficult to navigate the world of sports betting, which is where Kevin comes in to make it as simple as possible for you to pick a winner.