Southeast Missouri State vs. Southern Illinois CBB Predictions and Odds - Dec 15, 2021

College Basketball action continues on Wednesday at 8:00 PM EST as Southeast Missouri State takes on the favored Southern Illinois at SIU Arena.

Dimers' free betting picks for Southeast Missouri State vs. Southern Illinois, as well as our score prediction and best odds, are detailed below.

Who will win Southeast Missouri State vs. Southern Illinois?

Based on advanced computer power and data, Dimers.com has simulated Wednesday's Southeast Missouri State-Southern Illinois NCAA Basketball matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives Southern Illinois an 87% chance of defeating Southeast Missouri State.

MORE: Southeast Missouri State vs. Southern Illinois Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

Southern Illinois is currently the -13.5 favorite against Southeast Missouri State, with -110 at FanDuel Sportsbook the best odds available.

For the underdog Southeast Missouri State (+13.5) to cover the spread, FanDuel Sportsbook also has the best odds on the market at -110.

DraftKings Sportsbook has the best moneyline odds for Southern Illinois at -720, which means you can risk $720 to win $100, for a total payout of $820, if it gets the W.

Elsewhere, FanDuel Sportsbook has the best moneyline odds for Southeast Missouri State at +570, where you can bet $100 to profit $570, earning a total payout of $670, if it wins.

The Over/Under for total points scored is set at 133.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best College Basketball odds and lines.

According to DimersBOT, Southeast Missouri State (+13.5) is a 65% chance of covering the spread, while the Over/Under total of 133.5 points is considered an equal 50-50 chance of hitting.

MORE: Predictions for Every College Basketball Matchup

Best Bets for Southeast Missouri State vs. Southern Illinois

• Spread: Southeast Missouri State +13.5 at -110 with FanDuel Sportsbook (65% probability) 🔥
• Moneyline: Southern Illinois Win at -720 with DraftKings Sportsbook (87% probability)
• Over/Under: Under 133.5 at -110 with BetMGM (50% probability)

When you see a 🔥, that means you've found one of Dimers' best free picks today across all sports.

Southeast Missouri State vs. Southern Illinois Score Prediction

Dimers.com's predicted final score for Southeast Missouri State vs. Southern Illinois at SIU Arena this Wednesday has Southern Illinois winning 71-60.

Use our interactive widget below to see the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Southeast Missouri State-Southern Illinois matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this article for any changes to our betting insights ahead of Southeast Missouri State vs. Southern Illinois on Wednesday December 15, 2021.

Bet $1, Win $100 on Southeast Missouri State vs. Southern Illinois

How would you like to Bet $1, Win $100 if either Southeast Missouri State or Southern Illinois score a point on Wednesday? Of course you would!

Simply register with DraftKings Sportsbook via this exclusive link, deposit $5+, and place a $1 moneyline wager on Southeast Missouri State vs. Southern Illinois. If either team scores a point – yes, just a single point – you'll get $100 in Free Bets.

This promo is available to all new DraftKings Sportsbook users.

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as an online sportsbook), we may earn a referral fee.

Southeast Missouri State vs. Southern Illinois 2021 CBB Game Info

When does Southern Illinois play Southeast Missouri State in College Basketball?

• Date: Wednesday December 15, 2021
• Time: 8:00 PM EST / 5:00 PM PST
• Venue: SIU Arena

Ready to join an online sportsbook and start betting on College Basketball today? Check out the best sportsbook bonus offers in your state.

What other CBB games are on tonight?

Southeast Missouri State and Southern Illinois aren't the only two NCAA Basketball teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single CBB game in our College Basketball Bet Hub page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out today!