San Francisco 49ers vs. Kansas City Chiefs Prediction, Odds, NFL Picks - Super Bowl LVIII

San Francisco 49ers vs. Kansas City Chiefs Prediction, Odds, NFL Picks - Super Bowl LVIII

The Kansas City Chiefs will square off with the San Francisco 49ers in Super Bowl LVII at Allegiant Stadium on Sunday, commencing at 6:30PM ET.'s full preview for this week's 49ers vs. Chiefs matchup includes the latest betting odds, as well as our predictions and picks for the game.

Super Bowl LVIII Prediction: Model Picks 49ers To Cover The Spread

We have used trusted machine learning and statistics to simulate the outcome of Super Bowl LVIII between the 49ers and Chiefs 10,000 times, in keeping with our coverage of NFL predictions.

Our leading predictive analytics model gives the 49ers a 59% chance of beating the Chiefs, and our predicted final score has the 49ers winning 24-22.

According to our model, the 49ers (-1.5) have a 53% chance of covering the spread, while the 46.5-point Over/Under has an equal 50-50 chance of hitting.

Today's Super Bowl betting preview is proudly sponsored by BetMGM Sportsbook, which has an awesome Bet $5, Get $158 in Bonus Bets promo for new customers.

Super Bowl Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type 49ers Chiefs
Spread -1.5 (-110) +1.5 (-110)
Moneyline -120 +114
Total o46.5 (-115) u46.5 (-105)
  • The Chiefs are +1.5 underdogs versus the 49ers, with -110 at BetMGM Sportsbook the best odds currently available.
  • For the favored 49ers (-1.5) to cover the spread, DraftKings Sportsbook has the best odds currently on offer at -110.
  • FanDuel Sportsbook currently has the best moneyline odds for the Chiefs at +114. That means you can bet $100 to profit $114, earning a total payout of $214, if they win.
  • DraftKings currently has the best moneyline odds for the 49ers at -120, where you can risk $120 to win $100 for a total payout of $220 if they come out on top.
  • The Over/Under for total points scored sits at 46.5 with FanDuel, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

All odds are correct at the time of publication and are subject to change.

49ers vs. Chiefs Picks

Our predictions matched with the current odds reveal the top betting picks to make on Super Bowl LVIII, detailed in our our NFL best bets, crafted from expert modeling and analysis:

Bet Type Our Pick Best Odds
Spread 49ers -1.5 -110
Moneyline 49ers -120 🔥
Total Under 46.5 -105


49ers vs. Chiefs TD Scorers

Who will score an anytime touchdown in the 49ers vs. Chiefs Super Bowl?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first TD in the Super Bowl.

Our projections give McCaffrey a 20.5% chance of getting in for six first at Allegiant Stadium, while the 49ers RB is a 70.8% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player First TD Probability
Christian McCaffrey 20.5%
Deebo Samuel 8.1%
Brandon Aiyuk 7.8%
George Kittle 7.4%
Ray-Ray McCloud 2.1%

Kansas City Chiefs

Player First TD Probability
Isiah Pacheco 11.6%
Rashee Rice 8.3%
Travis Kelce 8.1%
Patrick Mahomes 3.2%
Marquez Valdes-Scantling 2.7%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player Anytime TD Probability
Christian McCaffrey 70.8%
Brandon Aiyuk 36.8%
Deebo Samuel 36.2%
George Kittle 33.3%
Ray-Ray McCloud 11.1%

Kansas City Chiefs

Player Anytime TD Probability
Isiah Pacheco 47.3%
Travis Kelce 37.6%
Rashee Rice 36.7%
Patrick Mahomes 16.8%
Marquez Valdes-Scantling 13.4%

49ers vs Chiefs Player Props

Here, you will find detailed projections for all of the key offensive players from the 49ers and Chiefs, including passing, rushing and receiving yards.

Super Bowl Starting Quarterbacks

Of the starting quarterbacks, the 49ers' Brock Purdy is projected to have a big game with 294 passing yards, while the Chiefs' Patrick Mahomes is expected to throw for a whopping 268 yards.

Player Proj. Pass Yards
Brock Purdy (SF) 294 yds
Patrick Mahomes (KC) 268 yds

49ers Rushing

Player Proj. Rush Yards
Christian McCaffrey 105 yds
Brock Purdy 12 yds
Deebo Samuel 11 yds

Chiefs Rushing

Player Proj. Rush Yards
Isiah Pacheco 79 yds
Patrick Mahomes 21 yds
Clyde Edwards-Helaire 9 yds

49ers Receiving

Player Proj. Rec. Yards
Brandon Aiyuk 70 yds
George Kittle 60 yds
Deebo Samuel 57 yds
Christian McCaffrey 38 yds
Jauan Jennings 21 yds

Chiefs Receiving

Player Proj. Rec. Yards
Rashee Rice 70 yds
Travis Kelce 69 yds
Marquez Valdes-Scantling 25 yds
Isiah Pacheco 18 yds
Justin Watson 18 yds

49ers vs. Chiefs Game Information

The Super Bowl game between the Chiefs and 49ers at Allegiant Stadium is scheduled to start at 6:30PM ET.


Our full betting coverage of 49ers vs. Chiefs includes pregame predictions, betting picks, and live win probabilities.


This article, enhanced by AI and automation, aims to deliver accurate 49ers vs. Chiefs insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. Remember to gamble responsibly—advice available at 1-800-GAMBLER. Note: Clicking links to our partners may earn us a referral fee.

More on NFL

Stay well-informed with the most recent NFL news and our analytics-driven NFL picks and parlays all season long. Plus, our Super Bowl odds give you the latest probabilities and the best available odds on the Super Bowl, AFC, NFC, and each division.

Ryan Leaver
Senior Sports and Sports Betting Editor

Ryan Leaver has long been entrenched in the world of sports and sports betting, now specializing in the NBA, NFL, college football, college basketball, and soccer. His passion shines through in his detailed game previews, best bets, props, and futures articles for both the NBA and NFL, along with his sharp prop bets for college football and insightful best bets for college basketball. Ryan’s expertise also extends to soccer, where he frequently offers practical betting tips and highlights the bets of the day. 

Known for his keen eye for valuable betting promos, Ryan adeptly guides bettors toward opportunities that enhance their wagering experiences. Collaborating often with DimersBOT, his articles are meticulously researched and offer savvy betting advice, making him a trusted source for sports bettors.

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