Red Sox vs. Yankees Prediction and Odds - Sep 24, 2022

MLB action continues on Saturday at 1:05PM ET as the Boston Red Sox lock horns with the New York Yankees at Yankee Stadium.

Domingo Germán (2-3, 3.12 ERA) will be on the bump for the Yankees, while the Red Sox are going with Nick Pivetta (10-11, 4.35 ERA).

Dimers' top betting picks for Red Sox vs. Yankees, as well as game predictions and best odds, are featured in this article.


Who will win Red Sox vs. Yankees?

Using trusted machine learning and data, has simulated Saturday's Red Sox-Yankees MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Yankees a 56% chance of getting the W against the Red Sox.

More: Free Betting Analysis for Red Sox vs. Yankees

Red Sox vs. Yankees Odds

  • Run Line: Yankees -1.5 (+130), Red Sox +1.5 (-142)
  • Moneyline: Yankees -155, Red Sox +138
  • Total: Over/Under 8.5 (+105/-110)

Run Line, Moneyline and Over/Under

The Yankees are listed as -1.5 favorites versus the Red Sox, with +130 at DraftKings Sportsbook the best odds currently available.

For the underdog Red Sox (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -142.

BetMGM currently has the best moneyline odds for the Yankees at -155, which means you can risk $155 to win $100, for a total payout of $255, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Red Sox at +138, where you can bet $100 to profit $138, earning a total payout of $238, if they win.

The Over/Under for total runs scored sits at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at +105, while FanDuel Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check all of the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Red Sox (+1.5) are a 60% chance of covering the run line, while the Over/Under total of 8.5 runs is a 53% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Red Sox vs. Yankees


If you see a 🔥, you know it's one of our best bets today across all major pro and college sports.

Our best bets are based on detailed modeling and wagering intelligence to serve you the best possible plays every time.

While the Yankees are more likely to win the game, according to DimersBOT, taking the Red Sox moneyline is the best option due to the 1.7% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published on is crucial to being a profitable bettor in the long run.

Red Sox vs. Yankees Prediction

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Dimers has full betting coverage of Saturday's Red Sox-Yankees matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates often, so refresh this page for the latest betting insights before Red Sox vs. Yankees on Saturday September 24, 2022.


Red Sox vs. Yankees 2022 Game Info

Saturday's game between the Yankees and Red Sox at Yankee Stadium is scheduled to commence at 1:05PM ET.

  • Who: Boston Red Sox vs. New York Yankees
  • Date: Saturday September 24, 2022
  • Time: 1:05PM ET / 10:05AM PT
  • Venue: Yankee Stadium

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What other MLB games are on today?

Now you've got the 411 on Red Sox vs. Yankees, take a look at the latest betting predictions for all upcoming MLB games in Dimers' MLB Bet Hub, where you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.

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