Pittsburgh Steelers vs. Los Angeles Chargers: Experts release early Week 10 predictions [2025]

The Pittsburgh Steelers and Los Angeles Chargers will meet in Week 10 of the NFL season at SoFi Stadium on Sunday, November 9, 2025, starting at 8:20PM ET.

Initial simulations from Dimers' trusted NFL model favor the Chargers as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Steelers vs. Chargers predictions page.

Pittsburgh vs. LA Chargers early predictions

Leveraging trusted machine learning and analysis, we have simulated the Steelers vs. Chargers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Steelers 41%, Chargers 59%
• Predicted final score: Steelers 21-23 Chargers
• Spread: Steelers (+3) 56%, Chargers (-3) 44%
• Total points (45.5): Over 50%, Under 50%

As of November 3, 2025, these Steelers-Chargers numbers and predictions reflect the latest data and insights available.

Steelers vs. Chargers Week 10 details

The NFL Week 10 game between the Chargers and Steelers at SoFi Stadium is scheduled for November 9, 2025.

• Who: Pittsburgh Steelers vs. Los Angeles Chargers
• Date: Sunday, November 9, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: SoFi Stadium

Steelers vs. Chargers opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Steelers +3 (-110), Chargers -3 (-106)
• Moneyline: Steelers +136, Chargers -148
• Total: Over/Under 45.5 (-105/-115)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 10 highlight the top candidates to score a TD in Steelers-Chargers in Week 10:

Pittsburgh Steelers

• Jaylen Warren: 46.5% probability
• DK Metcalf: 43.0% probability
• Kenneth Gainwell: 35.1% probability

Los Angeles Chargers

• Kimani Vidal: 58.5% probability
• Keenan Allen: 42.6% probability
• Quentin Johnston: 36.4% probability

Steelers vs Chargers player props

Jaylen Warren is projected to lead rushing for the Steelers, while Kimani Vidal is expected to pace the Chargers on the ground.

In the receiving game, our projections favor Pittsburgh's DK Metcalf and the LA Chargers' Ladd McConkey as the likely leaders for each team.

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Conclusion

We predict the Chargers, with a 59% win probability, will likely beat the Steelers in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Steelers vs. Chargers game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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