Philadelphia Eagles vs. Washington Commanders: Experts release early Week 16 predictions [2025]

The Philadelphia Eagles and Washington Commanders will meet in Week 16 of the NFL season at Northwest Stadium on Saturday, December 20, 2025, starting at 5:00PM ET.

Initial simulations from Dimers' trusted NFL model favor the Eagles as the most likely winner of this NFC East rivalry clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Eagles vs. Commanders predictions page.

Philadelphia vs. Washington early predictions

Leveraging trusted machine learning and analysis, we have simulated the Eagles vs. Commanders game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Eagles 65%, Commanders 35%
• Predicted final score: Eagles 24-21 Commanders
• Spread: Eagles (-5.5) 43%, Commanders (+5.5) 57%
• Total points (45.5): Over 53%, Under 47%

As of December 15, 2025, these Eagles-Commanders figures and predictions reflect the latest data and insights available.

Eagles vs. Commanders Week 16 details

The NFL Week 16 game between the Commanders and Eagles at Northwest Stadium is scheduled for December 20, 2025.

• Who: Philadelphia Eagles vs. Washington Commanders
• Date: Saturday, December 20, 2025
• Time: 5:00PM ET/2:00PM PT
• Venue: Northwest Stadium

Eagles vs. Commanders opening odds

We've researched the best betting odds across America for this Week 16 game, which are listed here:

• Spread: Eagles -5.5 (-110), Commanders +5.5 (-110)
• Moneyline: Eagles -250, Commanders +210
• Total: Over/Under 45.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

NFL Week 16 betting promos and codes

Make the most of Dimers' Eagles vs. Commanders predictions by exploring the two exciting offers below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket.

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.

Conclusion

We predict the Eagles, with a 65% win probability, will likely beat the Commanders in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Eagles vs. Commanders game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on NFL

Stay informed with the latest NFL betting news and data-led parlay picks all season long. Plus, our Super Bowl odds for top predictions and the best available odds on the Super Bowl, AFC, NFC and each division.