Colts vs. Cowboys Computer Picks, NFL Odds and Prediction for Sunday Night Football on December 4, 2022

Last updated: Dec 21, 2023, 6:10PM | Published: Dec 1, 2022, 2:02AM

The Dallas Cowboys begin their December tour of the AFC South this Sunday night when they host the Indianapolis Colts, who come off a short work week following a Monday night loss to the Pittsburgh Steelers. This one will be played at 8:20PM ET on December 4.

Dallas, meanwhile, has three extra days of rest compared to Indianapolis after playing on Thanksgiving and knocking off the New York Giants to move into sole possession of second place in the NFC East.

Find out how we think this one will play out in our Colts vs. Cowboys betting preview.

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Colts vs. Cowboys Computer Picks

Predictive Analytics Data

54% shot the Cowboys cover the -10.5 point spread
86% chance the Cowboys win on the moneyline
57% shot Colts-Cowboys goes Under 44.5

For the best NFL computer picks, check out our Colts vs. Cowboys data predictions. They are constantly updating based on hundreds of different data points.

Colts vs. Cowboys Odds and Betting Lines

Why Colts Will Cover The Spread

Keeping Matt Ryan upright against one of the best and most aggressive defenses in the NFL will go a long way for the visitors having a shot in this game come the fourth quarter.

Ryan was handed back controls of the offense almost instantly by interim head coach Jeff Saturday and has performed adequately in three straight starts. He 66 for 94 (70.2 percent) for 634 yards and two touchdowns with one interception plus a rushing score. He does have five games with multiple turnovers and that simply can’t happen this week if the Colts want to compete.

Why Cowboys Will Cover The Spread

The Cowboys’ red-hot offense aside, consider the days off between games here. There’s a huge difference between nine days without a game and five.

In addition, Dallas will be dialing up the defensive pressure against Colts veteran quarterback Ryan. The Cowboys lead the league in QB pressures as well as passing defense, allowing only 201.5 yards per game through the air, so Indianapolis is going to need a monster effort from Jonathan Taylor to be within single digits.

Why The Over Will Hit

Only one of the Colts’ first five road contests surpassed the Over and that was three weeks ago in Las Vegas. However, given how the Cowboys are rocking and rolling on offense, Indianapolis may not have to produce too much of its own.

Over the past four games, Dallas has put up 49, 28, 40 and 28 points after not scoring more than 25 in any of its first seven.

Why The Under Will Hit

A pair of top-10 defenses can always lead to a grinding type of game and the Colts will want no part of a track meet here considering the way the Cowboys are capable of rolling up points.

For as dynamic as the Dallas defense can be, opponents are averaging 132 yards per game on the ground, putting the Cowboys’ unit 22nd when it comes to stopping the run. That could mean a large dose of Taylor and lots of running clock.

Colts vs. Cowboys Prediction

Lean: Cowboys -11

The Colts are a solid defensive team but looked poor against Pittsburgh and will have their work cut out against a confidence Dallas offense. Indy also travels on a short week. This should be another big win for Big D.

Tony Bellissimo

Tony Bellissimo brings more than 25 years of sports reporting/editing experience to Dimers.com, as well as an extensive background covering all major professional sports, including 10 seasons (1998-2007) as NFL Editor of College & Pro Football Newsweekly. He's earned more than a dozen New York State Press Association awards, including Sports Writer of the Year (2nd place) in 2019, and oversees the sports coverage of 30 high schools and several colleges on Long Island.