New York Giants vs. New England Patriots: Experts release early Week 13 predictions [2025]

The New York Giants and New England Patriots will meet in Week 13 of the NFL season at Gillette Stadium on Monday, December 1, 2025, starting at 8:15PM ET.

Early simulations from Dimers' trusted NFL model favor the Patriots as the most likely winner of this cross-conference clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Giants vs. Patriots predictions page.

NY Giants vs. New England early predictions

Leveraging trusted machine learning and analysis, we have simulated the Giants vs. Patriots game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Giants 26%, Patriots 74%
• Predicted final score: Giants 19-26 Patriots
• Spread: Giants (+3) 56%, Patriots (-3) 44%
• Total points (42.5): Over 50%, Under 50%

As of November 24, 2025, these Giants-Patriots calculations and predictions reflect the latest data and insights available.

Giants vs. Patriots Week 13 details

The NFL Week 13 action between the Patriots and Giants at Gillette Stadium is scheduled for December 1, 2025.

• Who: New York Giants vs. New England Patriots
• Date: Monday, December 1, 2025
• Time: 8:15PM ET/5:15PM PT
• Venue: Gillette Stadium

Giants vs. Patriots opening odds

We've researched the best betting odds across America for this Week 13 game, which are listed here:

• Spread: Giants +3 (-105), Patriots -3 (-115)
• Moneyline: Giants +140, Patriots -166
• Total: Over/Under 42.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Patriots, with a 74% win probability, will likely beat the Giants in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Giants vs. Patriots game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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