New Orleans Saints vs. Carolina Panthers: Experts release early Week 10 predictions [2025]

The New Orleans Saints and Carolina Panthers will meet in Week 10 of the NFL season at Bank of America Stadium on Sunday, November 9, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Panthers as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Saints vs. Panthers predictions page.

New Orleans vs. Carolina early predictions

Leveraging trusted machine learning and analysis, we have simulated the Saints vs. Panthers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Saints 29%, Panthers 71%
• Predicted final score: Saints 17-22 Panthers
• Spread: Saints (+5.5) 50%, Panthers (-5.5) 50%
• Total points (40): Over 53%, Under 47%

As of November 3, 2025, these Saints-Panthers figures and predictions reflect the latest data and insights available.

Saints vs. Panthers Week 10 details

The NFL Week 10 game between the Panthers and Saints at Bank of America Stadium is scheduled for November 9, 2025.

• Who: New Orleans Saints vs. Carolina Panthers
• Date: Sunday, November 9, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Bank of America Stadium

Saints vs. Panthers opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Saints +5.5 (-110), Panthers -5.5 (-105)
• Moneyline: Saints +200, Panthers -238
• Total: Over/Under 40 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 10 highlight the top candidates to score a TD in Saints-Panthers in Week 10:

New Orleans Saints

• Chris Olave: 32.6% probability
• Rashid Shaheed: 29.5% probability
• Alvin Kamara: 25.6% probability

Carolina Panthers

• Tetairoa McMillan: 31.4% probability
• Rico Dowdle: 29.3% probability
• Xavier Legette: 23.0% probability

Saints vs Panthers player props

Alvin Kamara is projected to lead rushing for the Saints, while Rico Dowdle is expected to pace the Panthers on the ground.

In the receiving game, our projections favor New Orleans' Chris Olave and Carolina's Tetairoa McMillan as the likely leaders for each team.

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Conclusion

We predict the Panthers, with a 71% win probability, will likely beat the Saints in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Saints vs. Panthers game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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