MLB Thursday Betting Picks and Parlay - Apr 21, 2022

If you're a fan of daytime baseball then Thursday is a treat for you with a slate full of early games to pass the working day away. Is there anything better?

It's Thursday April 21, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for basketball bettors across the United States.

With MLB betting picks, probabilities, odds and predicted scores featured each and every day, check out our top plays for Thursday's MLB games.

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Free MLB Picks for Thursday April 21, 2022

White Sox vs. Guardians, 1:10PM ET

Dimers' data predictions gives the Guardians a 57% chance of winning this game straight up, while they are just 38% to cover the -1.5 runline. DimersBOT also has this one going OVER 8 total runs at a 56% probability. With that Total Runs line set at 8, this might be the PERFECT game to use the BetMGM Bet $10, Win $200 if there's a HR promo on! Click ➡️ here ⬅️ to get it!

Both Dylan Cease and Zach Plesac have had scintillating starts on the mound this season for the White Sox and Guardians respectively, but our projections say that's all about to change with two teams that combined for a 12 run blast in Game 1 of their doubleheader yesterday.

BET: Total runs OVER 8 (-110)

⚾️ White Sox vs. Guardians simulator
🔥 Betting Preview: White Sox vs. Guardians

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Yankees vs. Tigers, 1:10PM ET

Dimers' data predictions gives the Yankees a 79% chance of winning this game straight up, while they are also a 63% favorite to cover the -1.5 runline. DimersBOT also has this one going OVER 8.5 total runs at a 59% probability.

The Yankees have had their way with the usually awful Tigers this week, winning both games in the series thus far and covering the run line in each. We've got New York keeping that momentum rolling with yet another dominant performance.

BET: Yankees -1.5 (+104)

⚾️ Yankees vs. Tigers simulator
🔥 Betting Preview: Yankees vs. Tigers

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Giants vs. Mets, 1:10PM ET

Dimers' data predictions gives the Mets a 51% chance of winning this game straight up, while the Giants are a 65% favorite to cover the +1.5 runline. DimersBOT also has this one going UNDER 7.5 total runs at a 52% probability.

Carlos Carrasco is on the mound for the Mets and is coming up against a powerful batting lineup in the Giants - that doesn't bode well for Carrasco's poor first inning record. He's given up hits in the first innings in 10 of his last 11 games that he's started. That's going to give the SF hitters sufficient opportunities to get on base and convert to set themselves up early. 

BET: Giants 1st inning ML (+310)

⚾️ Giants vs. Mets simulator
🔥 Betting Preview: Giants vs. Mets

Your game not here? Find out who we're betting on for every baseball game on Thursday via our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.

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MLB Parlay for Thursday April 21, 2022

🔥 White Sox/Guardians o8 runs
🔥 Yankees -1.5
🔥 Giants first inning ML

💰 Parlay Odds +1489*

Tone's Take: Blue Jays vs. Red Sox

*All odds and lines correct at time of publishing

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