MLB Monday Player Prop Bets and Predictions - September 19, 2022

It's a new week and we're hunting for dingers with these home run plays for Monday.

It's Monday, September 19, 2022, and, as always, we've simulated all of the day's MLB games more than 10,000 times each to determine where the value lies for baseball bettors across the United States.

With MLB prop bets, probabilities and odds featured each and every day, make sure you check out our best player props for Monday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

Not with DraftKings yet? Well, sign up now and you'll get access to the best new customer MLB offer available. It's a bet $5 and get $100 no matter what offer, so simply click ➡️ here ⬅️, or tap the yellow button below.

Best MLB Prop Bets Today

Tigers vs. Orioles, 7:05PM ET

BET: Anthony Santander 1+ HR (+500)

We could see an avalanche of home runs tonight when the Orioles host the Tigers, with Tyler Alexander (3-10, 5.35 ERA) a pitcher to target for Detroit. Alexander has allowed 9 home runs in his last 6 starts. It's been a while since Anthony Santander hit one out of the park - two weeks to be exact - but he does come into this game in good form against left-handed pitching, batting at a .296 avg against lefties this season. With a dominant showing expected from the Orioles, we've got Santander being a contributing factor.

We're taking Anthony Santander  to hit a dinger with DraftKings Sportsbook. Click ➡️ here ⬅️ to bet.

⚾️ Tigers vs. Orioles Predictions
📈 Betting preview: Tigers vs. Orioles

Giants vs. Rockies, 8:40PM ET

BET: Thairo Estrada 1+ HR (+480)

Anyone betting dingers tonight needs to circle this game as one of interest with Chad Kuhl (6-9, 5.33 ERA) getting the start in the altitude of Coors Field for the Rockies. We bring it up almost every time he starts, but Kuhl has now gone 10 consecutive games giving up a home run. While San Francisco have had a year to forget and have been lacking in offensive prowess, we're looking at some major value tonight with Thairo Estrada. The Giants Infielder has perhaps been the most consistent hitter this month with a .283 avg to go along with 2 home runs. Estrada has an exceptional record against Kuhl as well, going 4-7 in previous career appearances.

The best place to bet on Thairo Estrada is with DraftKings Sportsbook. Click ➡️ here ⬅️ to get started and claim yourself a nice welcome bonus in the process!

⚾️ Giants vs. Rockies Predictions
📈 Betting preview: Giants vs. Rockies

Your game not here? Find out who we're betting on for every baseball game on Monday via our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section. 

MLB Prop Bets Parlay Today

There are a plethora of ways you can bet on MLB games, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $100 no matter what promo to guarantee a big cash.

Here's how to do it.

First, create your DraftKings account ➡️ here ⬅️, then make your first deposit of at least $5. Use that $5 to place a parlay using the below guys. If the parlay hits, you get a great payout, plus that 'no-matter-what' $100 bonus. If it doesn't, well, you've still got $100 of free cash from DraftKings just for betting on MLB. Win-win!

1️⃣ Santander HR
2️⃣ Estrada HR

MORE: Monday's MLB Picks and Parlay

*All odds subject to change from time of publishing