Louisville vs. Kentucky CFB Prediction and Odds - Nov 26, 2022

Last updated: Dec 21, 2023, 5:58PM | Published: Nov 21, 2022, 5:02AM

Kentucky and Louisville meet in College Football action at Kroger Field on Saturday, with kickoff at 3:00PM ET.

Dimers' top betting picks for Louisville vs. Kentucky, as well as game predictions and best odds, are detailed in this article.

Who will win Louisville vs. Kentucky?

Based on high-tech machine learning and data, Dimers.com has simulated Louisville vs. Kentucky 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Kentucky a 60% chance of beating Louisville.

More: Free Betting Analysis for Louisville vs. Kentucky

Louisville vs. Kentucky Game Odds

Spread: Kentucky -3.5 (-110), Louisville +3.5 (-110)
Moneyline: Kentucky -169, Louisville +155
Total: Over/Under 42.5 (-110/-110)

Point Spread, Moneyline and Over/Under

Kentucky is the -3.5 favorite against Louisville, with -110 at Caesars Sportsbook the best odds currently available.

For the underdog Louisville (+3.5) to cover the spread, Caesars Sportsbook also has the best odds currently on the market at -110.

Caesars Sportsbook currently has the best moneyline odds for Kentucky at -169. That means you can risk $169 to win $100, for a total payout of $269, if it gets the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for Louisville at +155, where you can bet $100 to profit $155, earning a total payout of $255, if it wins.

The Over/Under sits at 42.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all of the sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, the bookmakers have got it right and both Louisville and Kentucky are a 50% chance of covering the spread, while the Over/Under total of 42.5 points is a 54% chance of going Over.

More: Live Win Probabilities for All Major College Sports

Best Bets for Louisville vs. Kentucky

Spread: Louisville +3.5 @ -110 via Caesars Sportsbook (50% probability)
Moneyline: Louisville @ +155 via DraftKings Sportsbook (0.3% edge)
Total: Over 42.5 @ -110 via Caesars Sportsbook (54% probability)

Our best bets are based on world-class modeling and betting expertise to help you make better investments with the legal sportsbooks in the USA.

While Kentucky is more likely to win the game, according to DimersBOT, taking Louisville moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers is one of the keys to being a profitable sports bettor in the long run.

Louisville vs. Kentucky Prediction

Dimers.com's predicted final score for Louisville vs. Kentucky at Kroger Field on Saturday has Kentucky winning 24-20.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's Louisville-Kentucky matchup, including pregame predictions, computer picks, and live scores.

Remember, DimersBOT updates regularly, so check this article for the latest betting analysis before Louisville vs. Kentucky on Saturday November 26, 2022.

Louisville vs. Kentucky 2022 CFB Game Info

Saturday's game between Kentucky and Louisville in College Football at Kroger Field is scheduled to commence at 3:00PM ET.

Who: Louisville vs. Kentucky
Date: Saturday November 26, 2022
Time: 3:00PM ET / 12:00PM PT
Venue: Kroger Field

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Want more College Football predictions like this?

To get more NCAA Football betting predictions like you've just read for Louisville vs. Kentucky, all you've gotta do is visit our College Football Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the most comprehensive CFB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Kevin Hansen

Senior Sports Analyst

Kevin Hansen has a track record of delivering high-quality content. He writes about all sports, but his favorites are the NFL, NBA, MLB, and NHL. Kevin enjoys crunching the numbers and using data-driven insights to take on the sportsbooks. The majority of Kevin's time is spent writing about sports betting. His love for data and analytics drove him into the world of sports betting. Finding an edge in sports betting can take a long time, but Kevin believes it is well worth the effort. Kevin is just as passionate about sports as you are, and he empowers fellow bettors to become more educated through simple, actionable betting tips. It can be difficult to navigate the world of sports betting, which is where Kevin comes in to make it as simple as possible for you to pick a winner.