Los Angeles Rams vs. Carolina Panthers: Experts release early Week 13 preview [2025]

The Los Angeles Rams and Carolina Panthers will meet in Week 13 of the NFL season at Bank of America Stadium on Sunday, November 30, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Rams as the most likely winner of this NFC showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Rams vs. Panthers predictions page.

LA Rams vs. Carolina early predictions

Leveraging trusted machine learning and analysis, we have simulated the Rams vs. Panthers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Rams 82%, Panthers 18%
• Predicted final score: Rams 27-18 Panthers
• Spread: Rams (-10) 47%, Panthers (+10) 53%
• Total points (45.5): Over 49%, Under 51%

As of November 24, 2025, these Rams-Panthers numbers and predictions reflect the latest data and insights available.

Rams vs. Panthers Week 13 details

The NFL Week 13 matchup between the Panthers and Rams at Bank of America Stadium is scheduled for November 30, 2025.

• Who: Los Angeles Rams vs. Carolina Panthers
• Date: Sunday, November 30, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Bank of America Stadium

Rams vs. Panthers opening odds

We've researched the best betting odds across America for this Week 13 game, which are listed here:

• Spread: Rams -10 (-105), Panthers +10 (-110)
• Moneyline: Rams -600, Panthers +500
• Total: Over/Under 45.5 (-115/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Rams, with an 82% win probability, will likely beat the Panthers in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Rams vs. Panthers matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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