Los Angeles Angels vs. Houston Astros Prediction, Odds, MLB Picks [5/21/2024]

Los Angeles Angels vs. Houston Astros Prediction, Odds, MLB Picks [5/21/2024]

The Houston Astros will square off with the Los Angeles Angels in MLB action at Minute Maid Park on Tuesday, commencing at 8:10PM ET.

Cristian Javier (3-1, 3.23 ERA) will be the starting pitcher for the Astros, up against Griffin Canning (2-4, 5.21 ERA) for the Angels.

Dimers.com's full preview of Tuesday's Angels vs. Astros matchup includes our prediction, picks and the latest betting odds.

JOIN NOW: Dimers Pro unlocks +EV bets daily. We give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join Dimers Pro now for less than $1 a day!

Angels vs. Astros Prediction: Who Will Win, Cover the Run Line

We have used powerful machine learning and data to simulate the result of Tuesday's MLB matchup between the Angels and Astros 10,000 times, in keeping with our coverage of MLB predictions.

Our leading predictive analytics model gives the Astros a 62% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 56% chance of covering the run line, while the 9-run over/under has an equal 50-50 chance of hitting.

Angels vs. Astros Odds [5/21/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Angels Astros
Run Line +1.5 (-115) -1.5 (+100)
Moneyline +170 -196
Total o9 (-105) u9 (-114)

All odds are correct at the time of publication and are subject to change.

Angels vs. Astros Picks

At Dimers, our predictions, coupled with the best odds, reveal the top betting picks to place on every game, including Angels vs. Astros. Our MLB best bets are based on expert modeling and analysis, as you can see.

With a betting edge of 2.8%, a pick from the Angels vs. Astros game is featured in today's best bets on Dimers Pro.

Dimers Pro subscribers get hundreds of data-driven bets daily across thousands of games. Join now to get instant access and see the pick we have for this game.


Angels vs. Astros Game Information

Tuesday's MLB matchup between the Astros and Angels at Minute Maid Park is scheduled to begin at 8:10PM ET.


Our full betting coverage of the Angels vs. Astros includes pregame predictions, betting picks and live scores.

Calling Our Shot: Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.


We predict the Astros, with a 62% win probability, will likely beat the Angels on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on MLB

Stay updated with the most recent MLB betting news and our analytics-driven MLB picks and parlays all season long. Plus, our World Series odds give you the latest probabilities and the best available odds on the World Series, American League, National League, and each division.

Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua has a deep-rooted passion for sports and has been actively involved in sports betting for many years. Specializing in the MLB, NHL, NBA, MLS, and NFL, Jason delivers engaging game previews across these leagues. His expertise is particularly evident in his best bets for MLB, NHL, and college basketball. Additionally, Jason contributes valuable MLB and NFL props, as well as NBA first basket plays. 

Since joining Dimers in 2020 as the Head of Social and Community, Jason has also made significant contributions to the editorial department, offering daily articles that are not only well-researched but also deeply insightful. His strategic approach and collaboration with DimersBOT ensure his betting advice is top-notch.

On the socials
More from Dimers
About Dimers
icon 22,000+
Events covered per year
icon 8,000,000+
Our partners