Jacksonville Jaguars vs. Tennessee Titans: Experts release early Week 13 predictions [2025]

The Jacksonville Jaguars and Tennessee Titans will meet in Week 13 of the NFL season at Nissan Stadium on Sunday, November 30, 2025, starting at 1:00PM ET.

Initial simulations from Dimers' trusted NFL model favor the Jaguars as the most likely winner of this AFC South rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Jaguars vs. Titans predictions page.

Jacksonville vs. Tennessee early predictions

Leveraging trusted machine learning and analysis, we have simulated the Jaguars vs. Titans game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Jaguars 74%, Titans 26%
• Predicted final score: Jaguars 24-17 Titans
• Spread: Jaguars (-6.5) 50%, Titans (+6.5) 50%
• Total points (42.5): Over 48%, Under 52%

As of November 24, 2025, these Jaguars-Titans figures and predictions reflect the latest data and insights available.

Jaguars vs. Titans Week 13 details

The NFL Week 13 game between the Titans and Jaguars at Nissan Stadium is scheduled for November 30, 2025.

• Who: Jacksonville Jaguars vs. Tennessee Titans
• Date: Sunday, November 30, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Nissan Stadium

Jaguars vs. Titans opening odds

We've researched the best betting odds across America for this Week 13 game, which are listed here:

• Spread: Jaguars -6.5 (-108), Titans +6.5 (-104)
• Moneyline: Jaguars -325, Titans +290
• Total: Over/Under 42.5 (-105/-115)

Odds may continue to move—track live changes via our NFL odds page.

NFL Week 13 betting promos and codes

Make the most of Dimers' Jaguars vs. Titans predictions by exploring the two exciting offers below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket.

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.

Conclusion

We predict the Jaguars, with a 74% win probability, will likely beat the Titans in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Jaguars vs. Titans matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on NFL

Stay informed with the latest NFL betting news and data-led parlay picks all season long. Plus, our Super Bowl odds for top predictions and the best available odds on the Super Bowl, AFC, NFC and each division.