Green Bay Packers vs. Detroit Lions: Experts release early Week 13 predictions [2025]

The Green Bay Packers and Detroit Lions will meet in Week 13 of the NFL season at Ford Field on Thursday, November 27, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Lions as the most likely winner of this NFC North rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Packers vs. Lions predictions page.

Green Bay vs. Detroit early predictions

Leveraging trusted machine learning and analysis, we have simulated the Packers vs. Lions game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Packers 42%, Lions 58%
• Predicted final score: Packers 23-25 Lions
• Spread: Packers (+2.5) 42%, Lions (-2.5) 58%
• Total points (48.5): Over 53%, Under 47%

As of November 24, 2025, these Packers-Lions calculations and predictions reflect the latest data and insights available.

Packers vs. Lions Week 13 details

The NFL Week 13 game between the Lions and Packers at Ford Field is scheduled for November 27, 2025.

• Who: Green Bay Packers vs. Detroit Lions
• Date: Thursday, November 27, 2025 (Thanksgiving Day)
• Time: 1:00PM ET/10:00AM PT
• Venue: Ford Field

Packers vs. Lions opening odds

We've researched the best betting odds across America for this Week 13 game, which are listed here:

• Spread: Packers +2.5 (-102), Lions -2.5 (-110)
• Moneyline: Packers +130, Lions -140
• Total: Over/Under 48.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Lions, with a 58% win probability, will likely beat the Packers in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Packers vs. Lions matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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