Giants vs. Padres Prediction and Odds - Aug 10, 2022

MLB action continues on Wednesday at 4:10PM ET as the San Francisco Giants take on the San Diego Padres at PETCO Park.

Sean Manaea (6-6, 4.74 ERA) will get the ball for the Padres, while the Giants will counter with Jakob Junis (4-3, 3.05 ERA).

Dimers' best betting picks for Giants vs. Padres, as well as game predictions and betting odds, are detailed in this article.

Who will win Giants vs. Padres?

Using trusted computer power and data, Dimers.com has simulated Wednesday's Giants-Padres MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Padres a 59% chance of winning against the Giants.

More: Giants vs. Padres Simulated 10,000 Times

Giants vs. Padres Game Odds

• Run Line: Padres -1.5 (+125), Giants +1.5 (-145)
• Moneyline: Padres -160, Giants +140
• Total: Over/Under 9 (-110/-102)

Run Line, Moneyline and Over/Under

The Padres are currently -1.5 favorites versus the Giants, with +125 at DraftKings Sportsbook the best odds currently available.

For the underdog Giants (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -145.

BetMGM currently has the best moneyline odds for the Padres at -160, which means you can risk $160 to win $100, for a total payout of $260, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Giants at +140, where you can bet $100 to profit $140, earning a total payout of $240, if they win.

The Over/Under sits at 9 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -102.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 59% chance of covering the run line, while the 9-run Over/Under is a 51% chance of going Under.

More: Track Your Bets via Bet Center

Best Bets for Giants vs. Padres

• Run Line: Giants +1.5 @ -145 via Caesars Sportsbook (59% probability)
• Moneyline: Giants @ +140 via DraftKings Sportsbook
• Total: Under 9 @ -102 via FanDuel Sportsbook (51% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make better investments with your state's legal sportsbooks.

While the Padres are more likely to win the game, according to DimersBOT, betting on the Giants moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers is crucial to being a profitable sports bettor in the long run.

Giants vs. Padres Probabilities

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. San Diego, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Giants-Padres matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this article for any changes to our betting analysis ahead of Giants vs. Padres on Wednesday August 10, 2022.

Best Betting Promo for Giants vs. Padres

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Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may earn a referral fee.

Giants vs. Padres 2022 Game Info

Wednesday's game between the Padres and Giants at PETCO Park is scheduled to begin at 4:10PM ET.

• Who: San Diego Padres vs. San Francisco Giants
• Date: Wednesday August 10, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: PETCO Park

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What other MLB games are on today?

The Giants and Padres aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB matchup in our MLB Bet Hub page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.