Giants vs. Diamondbacks Prediction and Odds - Sep 24, 2022

The Arizona Diamondbacks square off with the San Francisco Giants in MLB action at Chase Field on Saturday, starting at 8:10PM ET.

The Diamondbacks will send Merrill Kelly (12-7, 3.15 ERA) to the mound, pitting him against Alex Cobb (6-6, 3.48 ERA) for the Giants.

Dimers' free betting picks for Giants vs. Diamondbacks, plus game predictions and betting odds, are featured in this article.


Who will win Giants vs. Diamondbacks?

Using cutting-edge computer power and data, has simulated Saturday's Giants-Diamondbacks MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Diamondbacks a 52% chance of winning against the Giants.

More: Giants vs. Diamondbacks Simulated 10K Times

Giants vs. Diamondbacks Current Odds

  • Run Line: Diamondbacks +1.5 (-200), Giants -1.5 (+170)
  • Moneyline: Diamondbacks -120, Giants +105
  • Total: Over/Under 7.5 (-102/-105)

Run Line, Moneyline and Over/Under

The Diamondbacks are +1.5 underdogs against the Giants, with -200 at BetMGM the best odds currently available.

For the favored Giants (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +170.

BetMGM currently has the best moneyline odds for the Diamondbacks at -120, which means you can risk $120 to win $100, for a total payout of $220, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Giants at +105, where you can bet $100 to profit $105, earning a total payout of $205, if they win.

The Over/Under is set at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -102, while BetMGM currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 65% chance of covering the run line, while the Over/Under total of 7.5 runs is a 55% chance of going Over.

More: Predictions for Every MLB Matchup

Best Bets for Giants vs. Diamondbacks


If you see a 🔥, you know it's one of our best free picks of the day across all sports.

Dimers' best bets are based on complex simulations and wagering intelligence to help you make more informed investments with the legal sportsbooks in your state.

While the Diamondbacks are more likely to win the game, according to DimersBOT, betting on the Giants moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at is one of the keys to achieving long-term profitability.

Giants vs. Diamondbacks Probabilities

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Dimers has full betting coverage of Saturday's Giants-Diamondbacks matchup, including pregame predictions, best betting picks, and live scores.

Remember, DimersBOT updates regularly, so check this page for the latest betting analysis before Giants vs. Diamondbacks on Saturday September 24, 2022.


Giants vs. Diamondbacks 2022 Game Info

Saturday's action between the Diamondbacks and Giants at Chase Field is scheduled to start at 8:10PM ET.

  • Who: San Francisco Giants vs. Arizona Diamondbacks
  • Date: Saturday September 24, 2022
  • Time: 8:10PM ET / 5:10PM PT
  • Venue: Chase Field

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