Free MLB Picks Today and Best Bets [Wednesday, 5/22/2024]

Free MLB Picks Today and Best Bets [Wednesday, 5/22/2024]

MLB betting is back for another great day, and we're here to bring you our top picks for Wednesday's baseball action.

Today's MLB best bets come from a range of matchups, including Angels vs. Astros and Brewers vs. Marlins.

Based on advanced simulations and machine learning, the bets featured below are led by an over/under play at 2:10PM ET.

For access to everything Dimers has to offer on Wednesday, May 22, 2024, check out Dimers Pro where you will get each of today's best bets, props and trends, as well our state-of-the-art parlay picker.


MLB Best Bets Today: 5/22/2024

After diving deep into the numbers and conducting thousands of simulations of today's action, DimersBOT, our famous predictive analytics model, has figured out the best baseball bets for upcoming games on Wednesday, May 22, 2024.

Keep in mind that the earliest game time is at the top of this list of picks. To get access to our full list of today's best bets, including customizable filters and sorting options, consider joining Dimers Pro.

Angels vs. Astros Over 9 Runs (+100)

Our model has pinpointed the next MLB betting opportunity today, which comes in the Angels vs. Astros matchup. We recommend an over/under bet on Over 9 Runs at +100 odds, which provides an edge of 2.4%.


MORE: MLB Best Bets

Brewers vs. Marlins Over 7 Runs (-102)

Our model has found another great MLB bet for Wednesday's baseball action, this time in the game between the Brewers and Marlins. We suggest placing an over/under wager on Over 7 Runs, available at -102 odds. Our analysis shows a compelling 3.0% edge for this bet.



Padres vs. Reds Under 9 Runs (+100)

  • Edge: 2.3%
  • Probability: 52.3%
  • Matchup: Padres vs. Reds (6:40PM ET, Wednesday)

Our next pick for Wednesday's baseball action comes from the Padres vs. Reds game. We recommend an over/under bet on Under 9 Runs, offered at attractive odds of +100. Our model indicates a favorable 2.3% edge for this wager.


MORE: Wednesday's MLB Trends

MLB Best Bets: Wednesday, 5/22/2024

As of 1:34PM ET, here are the next three MLB bets recommended by our model:

Matchup Bet Odds Edge
Angels vs. Astros Over 9 Runs +100 @ FanDuel 2.4%
Brewers vs. Marlins Over 7 Runs -102 @ DraftKings 3.0%
Padres vs. Reds Under 9 Runs +100 @ BetMGM 2.3%

Note: Clicking links to our sportsbook partners may earn us a referral fee.

While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to all of today's best bets identified by our model.

Wednesday's MLB picks are highlighted by a run line opportunity with a substantial 3.6% edge over the sportsbook odds.

To access these picks, along with a comprehensive range of props, trends and parlays for May 22, 2024, join Dimers Pro now.

Upcoming MLB Games to Bet On [5/22/2024]

More About MLB

This article is part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.


This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua has a deep-rooted passion for sports and has been actively involved in sports betting for many years. Specializing in the MLB, NHL, NBA, MLS, and NFL, Jason delivers engaging game previews across these leagues. His expertise is particularly evident in his best bets for MLB, NHL, and college basketball. Additionally, Jason contributes valuable MLB and NFL props, as well as NBA first basket plays. 

Since joining Dimers in 2020 as the Head of Social and Community, Jason has also made significant contributions to the editorial department, offering daily articles that are not only well-researched but also deeply insightful. His strategic approach and collaboration with DimersBOT ensure his betting advice is top-notch.

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