Detroit Lions vs. San Francisco 49ers Prediction, Odds, NFL Picks - NFC Championship Game [2024]

The San Francisco 49ers and Detroit Lions are scheduled to meet in the NFC Championship Game of the NFL Playoffs at Levi's Stadium on Sunday, starting at 6:30PM ET.

Dimers.com's comprehensive betting preview for Sunday's Lions vs. 49ers matchup includes the latest betting odds, as well as our predictions and picks for the game.

Lions vs. 49ers Prediction: Home Team Favored To Win By Model

We have used innovative machine learning and data analysis to simulate the outcome of Sunday's NFL matchup between the Lions and 49ers 10,000 times, in keeping with our coverage of NFL picks.

Our leading predictive analytics model gives the 49ers a 70% chance of defeating the Lions, and our predicted final score has the 49ers winning 28-22.

According to our model, the Lions (+7) have a 57% chance of covering the spread, while the 53.5-point Over/Under has a 56% chance of going under.

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Lions vs. 49ers Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Lions	49ers
Spread	+7 (+100)	-7 (-120)
Moneyline	+290	-340
Total	o53.5 (-105)	u53.5 (-112)

• The 49ers are currently -7 favorites versus the Lions, with -120 at BetMGM Sportsbook the best odds currently available.
• For the underdog Lions (+7) to cover the spread, BetMGM also has the best odds currently on offer at +100.
• DraftKings Sportsbook currently has the best moneyline odds for the 49ers at -340. That means you can risk $340 to win $100 for a total payout of $440 if they get the W.
• FanDuel Sportsbook currently has the best moneyline odds for the Lions at +290, where you can bet $100 to profit $290, earning a total payout of $390 if they win.
• The Over/Under for total points scored is set at 53.5 with FanDuel, which currently has the best odds for the Over at -105, while DraftKings currently has the best odds for the Under at -112.

All odds are correct at the time of publication and are subject to change.

As always, check out the sportsbooks you have access to in your state for the best NFL odds and lines.

Lions vs. 49ers Picks

By comparing our predictions to the odds listed above, we have determined the best betting picks to make on this game:

Bet Type	Our Pick	Best Odds
Spread	Lions +7	+100 🔥
Moneyline	Lions	+290 🔥
Total	Under 53.5	-112

Any time you see a 🔥, you know you've found one of our best free picks of the day across all major pro and college sports.

While the 49ers are more likely to win the game, betting on the Lions moneyline is the best option due to the 4.8% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is one of the keys to being a profitable bettor in the long run.

Our best NFL bets are based on world-class simulations and gambling intelligence to bring you the best possible plays every week of the season.

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Lions vs. 49ers TD Scorers

Who will score the first touchdown in Lions vs. 49ers?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first touchdown in Lions vs. 49ers.

Our projections give McCaffrey a 20.3% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 75.3% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Detroit Lions

Player	First TD Probability
Jahmyr Gibbs	8.9%
Amon-Ra St. Brown	7.7%
Sam LaPorta	7.1%
David Montgomery	7.1%
Jameson Williams	4.6%

San Francisco 49ers

Player	First TD Probability
Christian McCaffrey	20.3%
Deebo Samuel	9.0%
Brandon Aiyuk	8.6%
George Kittle	7.9%
Jauan Jennings	2.9%

Anytime Touchdown Scorer Predictions

Detroit Lions

Player	Anytime TD Probability
Jahmyr Gibbs	43.0%
Amon-Ra St. Brown	39.3%
Sam LaPorta	36.0%
David Montgomery	35.6%
Jameson Williams	24.5%

San Francisco 49ers

Player	Anytime TD Probability
Christian McCaffrey	75.3%
Deebo Samuel	43.1%
Brandon Aiyuk	41.6%
George Kittle	38.6%
Jauan Jennings	15.4%

Lions vs 49ers Player Props

Here, you will find detailed projections for all of the key offensive players from the Lions and 49ers, including passing, rushing and receiving yards.

Lions vs. 49ers Quarterbacks

Of the starting quarterbacks, the Lions' Jared Goff is projected to have a big game with 270 passing yards, while the 49ers' Brock Purdy is expected to throw for a whopping 341 yards.

Player	Proj. Pass Yards
Jared Goff (DET)	270 yds
Brock Purdy (SF)	341 yds

Lions Rushing

Player	Proj. Rush Yards
David Montgomery	54 yds
Jahmyr Gibbs	45 yds
Craig Reynolds	7 yds

49ers Rushing

Player	Proj. Rush Yards
Christian McCaffrey	111 yds
Deebo Samuel	12 yds
Brock Purdy	11 yds

Lions Receiving

Player	Proj. Rec. Yards
Amon-Ra St. Brown	96 yds
Sam LaPorta	53 yds
Jameson Williams	31 yds
Josh Reynolds	27 yds
Jahmyr Gibbs	17 yds

49ers Receiving

Player	Proj. Rec. Yards
Brandon Aiyuk	81 yds
George Kittle	68 yds
Deebo Samuel	61 yds
Christian McCaffrey	46 yds
Jauan Jennings	27 yds

Don't forget, our model updates regularly, so keep checking this article for the latest betting insights before the Lions vs. 49ers on Sunday January 28, 2024.

Lions vs. 49ers Game Information

Sunday's matchup between the 49ers and Lions at Levi's Stadium is scheduled to commence at 6:30PM ET.

• Who: Detroit Lions vs. San Francisco 49ers
• Date: Sunday January 28, 2024
• Time: 6:30PM ET / 3:30PM PT
• Venue: Levi's Stadium

Our full betting coverage of Lions vs. 49ers includes pregame predictions, betting picks, and live win probabilities.

How to Bet on Lions vs. 49ers

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Conclusion

This preview article has been partially generated using automated processes and AI technology. Our goal is to provide timely and accurate updates on this week's Lions vs. 49ers matchup, and automation assists in data collection, analysis, and formatting. Human editing and quality control are performed to ensure the content meets our editorial guidelines.

Dimers' predictions are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods. While these Lions vs. 49ers predictions can help you make informed decisions, it's important that you gamble responsibly and manage your bankroll effectively.

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