Cubs vs. Pirates Prediction and Odds - Sep 22, 2022Last updated: Sep 22, 2022, 11:01PM | Published: Sep 22, 2022, 8:33AM
The Pittsburgh Pirates and Chicago Cubs lock horns in MLB at PNC Park on Thursday, starting at 6:35PM ET.
The Pirates will have Mitch Keller (5-11, 4.03 ERA) start, up against Hayden Wesneski (1-1, 2.30 ERA) for the Cubs.
Dimers' free betting picks for Cubs vs. Pirates, plus game predictions and betting odds, are featured below.
Who will win Cubs vs. Pirates?
Using cutting-edge machine learning and data, Dimers.com has simulated Thursday's Cubs-Pirates MLB game 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, currently gives the Pirates a 53% chance of defeating the Cubs.
Cubs vs. Pirates Current Odds
- Run Line: Pirates +1.5 (-194), Cubs -1.5 (+170)
- Moneyline: Pirates -116, Cubs +100
- Total: Over/Under 7.5 (-105/-106)
Run Line, Moneyline and Over/Under
The Pirates are currently +1.5 underdogs against the Cubs, with -194 at FanDuel Sportsbook the best odds currently available.
For the favored Cubs (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +170.
FanDuel Sportsbook currently has the best moneyline odds for the Pirates at -116. That means you can risk $116 to win $100, for a total payout of $216, if they get the W.
Elsewhere, BetMGM currently has the best moneyline odds for the Cubs at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.
According to DimersBOT, the Pirates (+1.5) are a 67% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.
More: Best Prop Bets Today
Best Bets for Cubs vs. Pirates
- Run Line: Pirates +1.5 @ -194 via FanDuel Sportsbook (67% probability)
- Moneyline: Pirates @ -116 via FanDuel Sportsbook (53% probability)
- Total: Over 7.5 @ -105 via BetMGM (52% probability)
Our best bets are based on world-class modeling and gambling expertise to help you make more informed decisions with your state's legal sportsbooks.
Cubs vs. Pirates Betting Guide
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Dimers has full betting coverage of Thursday's Cubs-Pirates matchup, including pregame predictions, computer picks, and live win probabilities.
Don't forget, DimersBOT updates often, so keep an eye on this article for the latest betting insights ahead of Cubs vs. Pirates on Thursday September 22, 2022.
Cubs vs. Pirates 2022 Game Info
Thursday's game between the Pirates and Cubs at PNC Park is scheduled to begin at 6:35PM ET.
- Who: Chicago Cubs vs. Pittsburgh Pirates
- Date: Thursday September 22, 2022
- Time: 6:35PM ET / 3:35PM PT
- Venue: PNC Park
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Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!