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Clemson vs. South Carolina CFB Prediction and Odds - November 25, 2023

Clemson vs. South Carolina CFB Prediction and Odds - November 25, 2023

South Carolina takes on the favored Clemson in College Football action at Williams-Brice Stadium on Saturday, with kickoff at 7:30PM ET.

Dimers' full betting preview for Saturday's Clemson vs. South Carolina matchup includes the latest betting odds, as well as our predictions and best bets.

This Clemson vs. South Carolina prediction is brought to you by Bet365, which has a great Bet $5, Get $150 in Bonus Bets promo for new users.

Who Will Win: Clemson vs. South Carolina

Using trusted computer power and data, Dimers.com has simulated the outcome of Clemson vs. South Carolina 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives Clemson a 69% chance of beating South Carolina.

More: Get the latest College Football picks

Clemson vs. South Carolina Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Clemson South Carolina
Spread -7.5 (-110) +7.5 (-110)
Moneyline -315 +250
Total o47.5 (-110) u47.5 (-110)

Odds are correct at the time of publication and subject to change.

South Carolina is listed as the +7.5 underdog against Clemson, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Clemson (-7.5) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for South Carolina at +250. That means you can throw down $100 to profit $250, earning a total payout of $350, if it wins.

On the other hand, FanDuel Sportsbook also has the best moneyline odds for Clemson at -315, where you can risk $315 to win $100, for a total payout of $415, if it comes out on top.

The Over/Under is set at 47.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

According to DimersBOT, the bookmakers have got it right and both Clemson and South Carolina have a 50% chance of covering the spread, while the 47.5-point Over/Under also has a 58% chance of going Over.

As always, make sure you check all the online sports betting sites that are available in your state for the best College Football odds and lines.

Best Bets: Clemson vs. South Carolina

By comparing our predictions to the odds listed above, we have identified the best bets for this game:


If you see a 🔥, you know you've found one of our best free picks today across all major pro and college sports.

Dimers' best College Football bets are based on detailed simulations and gambling intelligence to serve you the best possible plays every time.

While Clemson is more likely to win the game, according to DimersBOT, taking South Carolina moneyline is the best option due to the 2.1% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers is one of the keys to achieving long-term profitability.

Calling all football fans! If you are yet to sign up with DraftKings Sportsbook, today is the day! Click here to sign up, and then place a $5 wager on Clemson vs. South Carolina to receive $150 in bonus bets, win or lose!

Clemson vs. South Carolina Prediction

Dimers.com's predicted final score for Clemson vs. South Carolina at Williams-Brice Stadium on Saturday has Clemson winning 29-21.

Click or tap on See Matchup for more information on Clemson vs. South Carolina.


Dimers has full betting coverage of this week's Clemson vs. South Carolina, including pregame predictions, betting picks, and live updates.

Don't forget, DimersBOT updates regularly, so refresh this article for the latest betting analysis ahead of Clemson vs. South Carolina on Saturday November 25, 2023.

Another great way to make the most of this Clemson vs. South Carolina game is by using the latest DraftKings promo, where a bet as small as $5 guarantees you $200 in bonus bets, plus an extra few SGP tokens.

Clemson vs. South Carolina Preview

Saturday's matchup between South Carolina and Clemson in College Football at Williams-Brice Stadium is scheduled to start at 7:30PM ET.

  • Who: Clemson vs. South Carolina
  • Date: Saturday November 25, 2023
  • Time: 7:30PM ET / 4:30PM PT
  • Venue: Williams-Brice Stadium

How to Bet on Clemson vs. South Carolina

Ready to join an online sportsbook and start betting on College Football today? We've listed the best available welcome offers for each and every legal betting state, including Bet365, where you get $150 in bonus bets for signing up and bettting $5 on Clemson vs. South Carolina.


This comprehensive betting preview features our Clemson vs. South Carolina prediction and College Football odds.

Dimers' picks and predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Clemson vs. South Carolina picks can help you make informed decisions, it's vital that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may receive a referral fee.

More on College Football

Stay well-informed on the current College Football betting news and our analytics-driven College Football picks and parlays all season long. Plus, our College Football National Championship odds give you the latest probabilities and the best available odds on the CFP, as well as each of the major conferences and divisions.

Kevin Hansen
Senior Sports Analyst

Kevin Hansen has a track record of delivering high-quality content. He writes about all sports, but his favorites are the NFL, NBA, MLB, and NHL. Kevin enjoys crunching the numbers and using data-driven insights to take on the sportsbooks. The majority of Kevin's time is spent writing about sports betting. His love for data and analytics drove him into the world of sports betting. Finding an edge in sports betting can take a long time, but Kevin believes it is well worth the effort. Kevin is just as passionate about sports as you are, and he empowers fellow bettors to become more educated through simple, actionable betting tips. It can be difficult to navigate the world of sports betting, which is where Kevin comes in to make it as simple as possible for you to pick a winner.

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