Clemson vs. South Carolina CFB Prediction and Odds - November 25, 2023

South Carolina takes on the favored Clemson in College Football action at Williams-Brice Stadium on Saturday, with kickoff at 7:30PM ET.

Dimers' full betting preview for Saturday's Clemson vs. South Carolina matchup includes the latest betting odds, as well as our predictions and best bets.

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Who Will Win: Clemson vs. South Carolina

Using trusted computer power and data, Dimers.com has simulated the outcome of Clemson vs. South Carolina 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives Clemson a 69% chance of beating South Carolina.

More: Get the latest College Football picks

Clemson vs. South Carolina Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Clemson	South Carolina
Spread	-7.5 (-110)	+7.5 (-110)
Moneyline	-315	+250
Total	o47.5 (-110)	u47.5 (-110)

Odds are correct at the time of publication and subject to change.

South Carolina is listed as the +7.5 underdog against Clemson, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Clemson (-7.5) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for South Carolina at +250. That means you can throw down $100 to profit $250, earning a total payout of $350, if it wins.

On the other hand, FanDuel Sportsbook also has the best moneyline odds for Clemson at -315, where you can risk $315 to win $100, for a total payout of $415, if it comes out on top.

The Over/Under is set at 47.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

According to DimersBOT, the bookmakers have got it right and both Clemson and South Carolina have a 50% chance of covering the spread, while the 47.5-point Over/Under also has a 58% chance of going Over.

As always, make sure you check all the online sports betting sites that are available in your state for the best College Football odds and lines.

Best Bets: Clemson vs. South Carolina

By comparing our predictions to the odds listed above, we have identified the best bets for this game:

• Spread: South Carolina +7.5 @ -110 via DraftKings Sportsbook (50% probability)
• Moneyline: South Carolina @ +250 via FanDuel Sportsbook (2.1% edge)
• Total: Over 47.5 @ -110 via FanDuel Sportsbook (58% probability) 🔥

If you see a 🔥, you know you've found one of our best free picks today across all major pro and college sports.

Dimers' best College Football bets are based on detailed simulations and gambling intelligence to serve you the best possible plays every time.

While Clemson is more likely to win the game, according to DimersBOT, taking South Carolina moneyline is the best option due to the 2.1% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers is one of the keys to achieving long-term profitability.

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Clemson vs. South Carolina Prediction

Dimers.com's predicted final score for Clemson vs. South Carolina at Williams-Brice Stadium on Saturday has Clemson winning 29-21.

Click or tap on See Matchup for more information on Clemson vs. South Carolina.

Dimers has full betting coverage of this week's Clemson vs. South Carolina, including pregame predictions, betting picks, and live updates.

Don't forget, DimersBOT updates regularly, so refresh this article for the latest betting analysis ahead of Clemson vs. South Carolina on Saturday November 25, 2023.

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Clemson vs. South Carolina Preview

Saturday's matchup between South Carolina and Clemson in College Football at Williams-Brice Stadium is scheduled to start at 7:30PM ET.

• Who: Clemson vs. South Carolina
• Date: Saturday November 25, 2023
• Time: 7:30PM ET / 4:30PM PT
• Venue: Williams-Brice Stadium

How to Bet on Clemson vs. South Carolina

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Conclusion

This comprehensive betting preview features our Clemson vs. South Carolina prediction and College Football odds.

Dimers' picks and predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Clemson vs. South Carolina picks can help you make informed decisions, it's vital that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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